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Research Article

The Calcitonin Receptor Gene Is a Candidate for Regulation of Susceptibility to Herpes simplex Type 1 Neuronal Infection Leading to Encephalitis in Rat

  • Nada Abdelmagid mail,

    nada.abdelmagid@ki.se

    Affiliation: Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

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  • Biborka Bereczky-Veress,

    Affiliations: Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, Department of Medicine, Infectious Disease Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

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  • André Ortlieb Guerreiro-Cacais,

    Affiliation: Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

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  • Petra Bergman,

    Affiliation: Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

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  • Katarina M. Luhr,

    Affiliation: Department of Neuroscience, Neurodegenerative Diseases Unit, Karolinska Institutet, Stockholm, Sweden

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  • Tomas Bergström,

    Affiliation: Department of Clinical Virology, Göteborgs Universitet, Göteborg, Sweden

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  • Birgit Sköldenberg,

    Affiliation: Department of Medicine, Infectious Disease Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

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  • Fredrik Piehl,

    Affiliation: Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

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  • Tomas Olsson equal contributor,

    equal contributor Contributed equally to this work with: Tomas Olsson, Margarita Diez

    Affiliation: Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

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  • Margarita Diez equal contributor

    equal contributor Contributed equally to this work with: Tomas Olsson, Margarita Diez

    Affiliation: Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

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  • Published: June 28, 2012
  • DOI: 10.1371/journal.ppat.1002753

About the Authors

Nada Abdelmagid, Biborka Bereczky-Veress, André Ortlieb Guerreiro-Cacais, Petra Bergman, Fredrik Piehl, Tomas Olsson, Margarita Diez
Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
Biborka Bereczky-Veress, Birgit Sköldenberg
Department of Medicine, Infectious Disease Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
Katarina M. Luhr
Department of Neuroscience, Neurodegenerative Diseases Unit, Karolinska Institutet, Stockholm, Sweden
Tomas Bergström
Department of Clinical Virology, Göteborgs Universitet, Göteborg, Sweden

Corresponding Author

Email: nada.abdelmagid@ki.se

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NA BBV AOGC FP TO MD. Performed the experiments: NA BBV AOGC PB KML MD. Analyzed the data: NA BBV AOGC PB BS FP TO MD. Contributed reagents/materials/analysis tools: TB FP TO MD. Wrote the paper: NA BBV AOGC PB FP TO MD.