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Research Article

Conditional Stat1 Ablation Reveals the Importance of Interferon Signaling for Immunity to Listeria monocytogenes Infection

  • Elisabeth Kernbauer,

    Affiliation: Max F. Perutz Laboratories, University of Vienna, Vienna, Austria

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  • Verena Maier,

    Affiliation: Max F. Perutz Laboratories, University of Vienna, Vienna, Austria

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  • Dagmar Stoiber,

    Affiliations: Ludwig Boltzmann Institute for Cancer Research (LBI-CR), Vienna, Austria, Institute of Pharmacology, Centre for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria

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  • Birgit Strobl,

    Affiliation: Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, Austria

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  • Christine Schneckenleithner,

    Affiliation: Institute of Pharmacology and Toxicology, University of Veterinary Medicine Vienna, Vienna, Austria

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  • Veronika Sexl,

    Affiliation: Institute of Pharmacology and Toxicology, University of Veterinary Medicine Vienna, Vienna, Austria

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  • Ursula Reichart,

    Affiliation: Biomodels Austria, University of Veterinary Medicine Vienna, Vienna, Austria

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  • Boris Reizis,

    Affiliation: Department of Microbiology and Immunology, Columbia University Medical Center, New York, New York, United States of America

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  • Ulrich Kalinke,

    Affiliation: Twincore, Center for Experimental and Clinical Infection Research, Hannover, Germany

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  • Amanda Jamieson,

    Affiliation: Max F. Perutz Laboratories, University of Vienna, Vienna, Austria

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  • Mathias Müller,

    Affiliation: Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, Austria

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  • Thomas Decker mail

    thomas.decker@univie.ac.at

    Affiliation: Max F. Perutz Laboratories, University of Vienna, Vienna, Austria

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  • Published: June 14, 2012
  • DOI: 10.1371/journal.ppat.1002763

About the Authors

Elisabeth Kernbauer, Verena Maier, Amanda Jamieson, Thomas Decker
Max F. Perutz Laboratories, University of Vienna, Vienna, Austria
Dagmar Stoiber
Ludwig Boltzmann Institute for Cancer Research (LBI-CR), Vienna, Austria
Dagmar Stoiber
Institute of Pharmacology, Centre for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria
Birgit Strobl, Mathias Müller
Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, Austria
Christine Schneckenleithner, Veronika Sexl
Institute of Pharmacology and Toxicology, University of Veterinary Medicine Vienna, Vienna, Austria
Ursula Reichart
Biomodels Austria, University of Veterinary Medicine Vienna, Vienna, Austria
Boris Reizis
Department of Microbiology and Immunology, Columbia University Medical Center, New York, New York, United States of America
Ulrich Kalinke
Twincore, Center for Experimental and Clinical Infection Research, Hannover, Germany

Corresponding Author

Email: thomas.decker@univie.ac.at

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: VS MM TD EK AJ DS BS. Performed the experiments: EK VM CS UR. Analyzed the data: EK TD MM VS. Contributed reagents/materials/analysis tools: UK BR. Wrote the paper: EK TD AJ.