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Research Article

Tc17 Cells Mediate Vaccine Immunity against Lethal Fungal Pneumonia in Immune Deficient Hosts Lacking CD4+ T Cells

  • Som Gowda Nanjappa,

    Affiliation: The Department of Pediatrics, School of Medicine and Public Health, University of Wisconsin Madison, Madison, Wisconsin, United States of America

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  • Erika Heninger,

    Affiliation: The Department of Pediatrics, School of Medicine and Public Health, University of Wisconsin Madison, Madison, Wisconsin, United States of America

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  • Marcel Wüthrich,

    Affiliation: The Department of Pediatrics, School of Medicine and Public Health, University of Wisconsin Madison, Madison, Wisconsin, United States of America

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  • David Joseph Gasper,

    Affiliation: The Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin Madison, Madison, Wisconsin, United States of America

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  • Bruce S. Klein mail

    bsklein@wisc.edu

    Affiliations: The Department of Pediatrics, School of Medicine and Public Health, University of Wisconsin Madison, Madison, Wisconsin, United States of America, The Department of Internal Medicine, School of Medicine and Public Health, University of Wisconsin Madison, Madison, Wisconsin, United States of America, The Department of Medical Microbiology and Immunology, School of Medicine and Public Health, University of Wisconsin Madison, Madison, Wisconsin, United States of America

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  • Published: July 19, 2012
  • DOI: 10.1371/journal.ppat.1002771

About the Authors

Som Gowda Nanjappa, Erika Heninger, Marcel Wüthrich, Bruce S. Klein
The Department of Pediatrics, School of Medicine and Public Health, University of Wisconsin Madison, Madison, Wisconsin, United States of America
David Joseph Gasper
The Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin Madison, Madison, Wisconsin, United States of America
Bruce S. Klein
The Department of Internal Medicine, School of Medicine and Public Health, University of Wisconsin Madison, Madison, Wisconsin, United States of America
Bruce S. Klein
The Department of Medical Microbiology and Immunology, School of Medicine and Public Health, University of Wisconsin Madison, Madison, Wisconsin, United States of America

Corresponding Author

Email: bsklein@wisc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SGN MW BK. Performed the experiments: SGN EH MW DG. Analyzed the data: SGN EH MW DG BK. Wrote the paper: SGN BK.