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Research Article

GogB Is an Anti-Inflammatory Effector that Limits Tissue Damage during Salmonella Infection through Interaction with Human FBXO22 and Skp1

  • Ana Victoria C. Pilar,

    Affiliation: Michael G. DeGroote Institute for Infectious Disease Research and the Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada

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  • Sarah A. Reid-Yu,

    Affiliation: Michael G. DeGroote Institute for Infectious Disease Research and the Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada

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  • Colin A. Cooper,

    Affiliation: Michael G. DeGroote Institute for Infectious Disease Research and the Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada

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  • David T. Mulder,

    Affiliation: Michael G. DeGroote Institute for Infectious Disease Research and the Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada

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  • Brian K. Coombes mail

    coombes@mcmaster.ca

    Affiliation: Michael G. DeGroote Institute for Infectious Disease Research and the Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada

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  • Published: June 28, 2012
  • DOI: 10.1371/journal.ppat.1002773

About the Authors

Ana Victoria C. Pilar, Sarah A. Reid-Yu, Colin A. Cooper, David T. Mulder, Brian K. Coombes
Michael G. DeGroote Institute for Infectious Disease Research and the Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada

Corresponding Author

Email: coombes@mcmaster.ca

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AVCP SAR BKC. Performed the experiments: AVCP SAR CAC. Analyzed the data: AVCP SAR CAC BKC. Contributed reagents/materials/analysis tools: DTM. Wrote the paper: AVCP BKC.