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Research Article

Natural Transformation Facilitates Transfer of Transposons, Integrons and Gene Cassettes between Bacterial Species

  • Sara Domingues,

    Affiliations: Centre of Pharmaceutical Studies, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal, Department of Pharmacy, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway

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  • Klaus Harms,

    Affiliation: Department of Pharmacy, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway

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  • W. Florian Fricke,

    Affiliation: Institute for Genome Sciences, University of Maryland, School of Medicine, Baltimore, Maryland, United States of America

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  • Pål J. Johnsen,

    Affiliation: Department of Pharmacy, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway

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  • Gabriela J. da Silva,

    Affiliation: Centre of Pharmaceutical Studies, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal

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  • Kaare Magne Nielsen mail

    kaare.nielsen@uit.no

    Affiliations: Department of Pharmacy, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway, Genøk-Centre for Biosafety, Tromsø, Norway

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  • Published: August 02, 2012
  • DOI: 10.1371/journal.ppat.1002837

About the Authors

Sara Domingues, Gabriela J. da Silva
Centre of Pharmaceutical Studies, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal
Sara Domingues, Klaus Harms, Pål J. Johnsen, Kaare Magne Nielsen
Department of Pharmacy, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway
W. Florian Fricke
Institute for Genome Sciences, University of Maryland, School of Medicine, Baltimore, Maryland, United States of America
Kaare Magne Nielsen
Genøk-Centre for Biosafety, Tromsø, Norway

Corresponding Author

Email: kaare.nielsen@uit.no

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SD KH PJJ GJdS KMN. Performed the experiments: SD KH WFF. Analyzed the data: SD WFF. Wrote the paper: SD GJdS KMN.