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Research Article

Bap, a Biofilm Matrix Protein of Staphylococcus aureus Prevents Cellular Internalization through Binding to GP96 Host Receptor

  • Jaione Valle,

    Affiliation: Laboratory of Microbial Biofilms, Idab-Universidad Pública de Navarra-CSIC-Gobierno de Navarra, Pamplona, Spain

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  • Cristina Latasa,

    Affiliation: Laboratory of Microbial Biofilms, Idab-Universidad Pública de Navarra-CSIC-Gobierno de Navarra, Pamplona, Spain

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  • Carmen Gil,

    Affiliation: Laboratory of Microbial Biofilms, Idab-Universidad Pública de Navarra-CSIC-Gobierno de Navarra, Pamplona, Spain

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  • Alejandro Toledo-Arana,

    Affiliation: Laboratory of Microbial Biofilms, Idab-Universidad Pública de Navarra-CSIC-Gobierno de Navarra, Pamplona, Spain

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  • Cristina Solano,

    Affiliation: Laboratory of Microbial Biofilms, Idab-Universidad Pública de Navarra-CSIC-Gobierno de Navarra, Pamplona, Spain

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  • José R. Penadés,

    Affiliation: Instituto de Biomedicina de Valencia (IBV-CSIC), Valencia, Spain

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  • Iñigo Lasa mail

    ilasa@unavarra.es

    Affiliation: Laboratory of Microbial Biofilms, Idab-Universidad Pública de Navarra-CSIC-Gobierno de Navarra, Pamplona, Spain

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  • Published: August 02, 2012
  • DOI: 10.1371/journal.ppat.1002843

About the Authors

Jaione Valle, Cristina Latasa, Carmen Gil, Alejandro Toledo-Arana, Cristina Solano, Iñigo Lasa
Laboratory of Microbial Biofilms, Idab-Universidad Pública de Navarra-CSIC-Gobierno de Navarra, Pamplona, Spain
José R. Penadés
Instituto de Biomedicina de Valencia (IBV-CSIC), Valencia, Spain

Corresponding Author

Email: ilasa@unavarra.es

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JV IL. Performed the experiments: JV CL CG CS ATA. Analyzed the data: JV ATA CS JRP IL. Contributed reagents/materials/analysis tools: JV JRP IL. Wrote the paper: JV IL.