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Research Article

Vector-Borne Transmission Imposes a Severe Bottleneck on an RNA Virus Population

  • Naomi L. Forrester,

    Affiliation: Institute for Human Infections and Immunity, Center for Biodefense and Emerging Infectious Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America

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  • Mathilde Guerbois,

    Affiliation: Institute for Human Infections and Immunity, Center for Biodefense and Emerging Infectious Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America

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  • Robert L. Seymour,

    Affiliation: Institute for Human Infections and Immunity, Center for Biodefense and Emerging Infectious Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America

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  • Heidi Spratt,

    Affiliation: Sealy Center for Preventative Medicine and Preventative Medicine and Community Health, University of Texas Medical Branch, Galveston, Texas, United States of America

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  • Scott C. Weaver mail

    sweaver@utmb.edu

    Affiliation: Institute for Human Infections and Immunity, Center for Biodefense and Emerging Infectious Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America

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  • Published: September 13, 2012
  • DOI: 10.1371/journal.ppat.1002897

About the Authors

Naomi L. Forrester, Mathilde Guerbois, Robert L. Seymour, Scott C. Weaver
Institute for Human Infections and Immunity, Center for Biodefense and Emerging Infectious Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America
Heidi Spratt
Sealy Center for Preventative Medicine and Preventative Medicine and Community Health, University of Texas Medical Branch, Galveston, Texas, United States of America

Corresponding Author

Email: sweaver@utmb.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NLF SCW. Performed the experiments: NLF MG RLS. Analyzed the data: NLF HS. Wrote the paper: NLF SCW.