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Research Article

Real-time Transcriptional Profiling of Cellular and Viral Gene Expression during Lytic Cytomegalovirus Infection

  • Lisa Marcinowski,

    Affiliation: Max von Pettenkofer-Institute, Ludwig-Maximilians-University, Munich, Germany

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  • Michael Lidschreiber,

    Affiliation: Gene Center and Department of Biochemistry, Ludwig-Maximilians-University, Munich, Germany

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  • Lukas Windhager,

    Affiliation: Institute for Informatics, Ludwig-Maximilians-University, Munich, Germany

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  • Martina Rieder,

    Affiliation: Max von Pettenkofer-Institute, Ludwig-Maximilians-University, Munich, Germany

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  • Jens B. Bosse,

    Affiliation: Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America

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  • Bernd Rädle,

    Affiliation: Max von Pettenkofer-Institute, Ludwig-Maximilians-University, Munich, Germany

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  • Thomas Bonfert,

    Affiliation: Institute for Informatics, Ludwig-Maximilians-University, Munich, Germany

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  • Ildiko Györy,

    Affiliation: School of Biomedical and Biological Sciences, Centre for Research in Translational Biomedicine, Plymouth University, Plymouth, United Kingdom

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  • Miranda de Graaf,

    Affiliation: Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom

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  • Olivia Prazeres da Costa,

    Affiliation: Institute for Microbiology, Immunology and Hygiene, Technical University, Munich, Germany

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  • Philip Rosenstiel,

    Affiliation: Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany

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  • Caroline C. Friedel,

    Affiliation: Institute for Informatics, Ludwig-Maximilians-University, Munich, Germany

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  • Ralf Zimmer,

    Affiliation: Institute for Informatics, Ludwig-Maximilians-University, Munich, Germany

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  • Zsolt Ruzsics,

    Affiliation: Max von Pettenkofer-Institute, Ludwig-Maximilians-University, Munich, Germany

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  • Lars Dölken mail

    ld408@medschl.cam.ac.uk

    Affiliations: Max von Pettenkofer-Institute, Ludwig-Maximilians-University, Munich, Germany, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom

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  • Published: September 06, 2012
  • DOI: 10.1371/journal.ppat.1002908

About the Authors

Lisa Marcinowski, Martina Rieder, Bernd Rädle, Zsolt Ruzsics, Lars Dölken
Max von Pettenkofer-Institute, Ludwig-Maximilians-University, Munich, Germany
Michael Lidschreiber
Gene Center and Department of Biochemistry, Ludwig-Maximilians-University, Munich, Germany
Lukas Windhager, Thomas Bonfert, Caroline C. Friedel, Ralf Zimmer
Institute for Informatics, Ludwig-Maximilians-University, Munich, Germany
Jens B. Bosse
Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America
Ildiko Györy
School of Biomedical and Biological Sciences, Centre for Research in Translational Biomedicine, Plymouth University, Plymouth, United Kingdom
Miranda de Graaf, Lars Dölken
Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom
Olivia Prazeres da Costa
Institute for Microbiology, Immunology and Hygiene, Technical University, Munich, Germany
Philip Rosenstiel
Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany

Corresponding Author

Email: ld408@medschl.cam.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LM ZR LD. Performed the experiments: LM ML LW MR JBB BR MDG PR. Analyzed the data: LM ML LW TB IG OP CCF RZ ZR LD. Contributed reagents/materials/analysis tools: MR JBB IG OP PR. Wrote the paper: LM LD.