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Research Article

Slc15a4, a Gene Required for pDC Sensing of TLR Ligands, Is Required to Control Persistent Viral Infection

  • Amanda L. Blasius,

    Affiliation: Departments of Genetics and Immunology, The Scripps Research Institute, La Jolla, California, United States of America

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  • Philippe Krebs,

    Affiliations: Departments of Genetics and Immunology, The Scripps Research Institute, La Jolla, California, United States of America, Institute of Pathology, University of Bern, Bern, Switzerland

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  • Brian M. Sullivan,

    Affiliation: Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

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  • Michael B. Oldstone,

    Affiliation: Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

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  • Daniel L. Popkin mail

    daniel.popkin@case.edu

    Affiliations: Departments of Genetics and Immunology, The Scripps Research Institute, La Jolla, California, United States of America, Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America, Departments of Dermatology, Pathology, Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, Ohio, United States of America

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  • Published: September 13, 2012
  • DOI: 10.1371/journal.ppat.1002915

About the Authors

Amanda L. Blasius, Philippe Krebs, Daniel L. Popkin
Departments of Genetics and Immunology, The Scripps Research Institute, La Jolla, California, United States of America
Philippe Krebs
Institute of Pathology, University of Bern, Bern, Switzerland
Brian M. Sullivan, Michael B. Oldstone, Daniel L. Popkin
Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America
Daniel L. Popkin
Departments of Dermatology, Pathology, Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, Ohio, United States of America

Corresponding Author

Email: daniel.popkin@case.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ALB PK DLP. Performed the experiments: ALB PK BMS DLP. Analyzed the data: ALB PK BMS DLP. Contributed reagents/materials/analysis tools: DLP MBO. Wrote the paper: ALB PK DLP.