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Research Article

Very Long O-antigen Chains Enhance Fitness during Salmonella-induced Colitis by Increasing Bile Resistance

  • Robert W. Crawford,

    Affiliation: Department of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, Davis, California, United States of America

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  • A. Marijke Keestra,

    Affiliation: Department of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, Davis, California, United States of America

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  • Sebastian E. Winter,

    Affiliation: Department of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, Davis, California, United States of America

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  • Mariana N. Xavier,

    Affiliation: Department of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, Davis, California, United States of America

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  • Renée M. Tsolis,

    Affiliation: Department of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, Davis, California, United States of America

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  • Vladimir Tolstikov,

    Affiliation: Metabolomics Core Laboratory, Genome Center, University of California at Davis, Davis, California, United States of America

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  • Andreas J. Bäumler mail

    ajbaumler@ucdavis.edu

    Affiliation: Department of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, Davis, California, United States of America

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  • Published: September 20, 2012
  • DOI: 10.1371/journal.ppat.1002918

About the Authors

Robert W. Crawford, A. Marijke Keestra, Sebastian E. Winter, Mariana N. Xavier, Renée M. Tsolis, Andreas J. Bäumler
Department of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, Davis, California, United States of America
Vladimir Tolstikov
Metabolomics Core Laboratory, Genome Center, University of California at Davis, Davis, California, United States of America

Corresponding Author

Email: ajbaumler@ucdavis.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RWC AMK SEW RMT AJB. Performed the experiments: RWC AMK SEW MNX VT AJB. Analyzed the data: RWC AMK SEW MNX RMT VT AJB. Contributed reagents/materials/analysis tools: VT. Wrote the paper: RWC VT AJB.