# wombat urls ß PLOS Pathogens: AID Activity in B Cells Strongly Correlates with Polyclonal Antibody Affinity Maturation in-vivo Following Pandemic 2009-H1N1 Vaccination in Humans
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Research Article

AID Activity in B Cells Strongly Correlates with Polyclonal Antibody Affinity Maturation in-vivo Following Pandemic 2009-H1N1 Vaccination in Humans

  • Surender Khurana mail,

    surender.khurana@fda.hhs.gov (SK); hana.golding@fda.hhs.gov (HG)

    Affiliation: Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration (FDA), Bethesda, Maryland, United States of America

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  • Daniela Frasca,

    Affiliation: Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, Florida, United States of America

    X
  • Bonnie Blomberg,

    Affiliation: Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, Florida, United States of America

    X
  • Hana Golding mail

    surender.khurana@fda.hhs.gov (SK); hana.golding@fda.hhs.gov (HG)

    Affiliation: Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration (FDA), Bethesda, Maryland, United States of America

    X
  • Published: September 13, 2012
  • DOI: 10.1371/journal.ppat.1002920

About the Authors

Surender Khurana, Hana Golding
Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration (FDA), Bethesda, Maryland, United States of America
Daniela Frasca, Bonnie Blomberg
Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, Florida, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SK DF BB HG. Performed the experiments: SK DF. Analyzed the data: SK DF BB HG. Contributed reagents/materials/analysis tools: SK DF BB. Wrote the paper: SK HG.