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Research Article

Kaposi's Sarcoma Herpesvirus K15 Protein Contributes to Virus-Induced Angiogenesis by Recruiting PLCγ1 and Activating NFAT1-dependent RCAN1 Expression

  • Kiran Bala,

    Affiliation: Institute of Virology, Hannover Medical School, Hannover, Germany

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  • Raffaella Bosco,

    Affiliation: Institute of Virology, Hannover Medical School, Hannover, Germany

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  • Silvia Gramolelli,

    Affiliation: Institute of Virology, Hannover Medical School, Hannover, Germany

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  • Darya A. Haas,

    Affiliation: Institute of Virology, Hannover Medical School, Hannover, Germany

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  • Semra Kati,

    Affiliation: Institute of Virology, Hannover Medical School, Hannover, Germany

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  • Marcel Pietrek,

    Affiliation: Institute of Virology, Hannover Medical School, Hannover, Germany

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  • Anika Hävemeier,

    Affiliation: Institute of Virology, Hannover Medical School, Hannover, Germany

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  • Yuri Yakushko,

    Affiliation: Institute of Virology, Hannover Medical School, Hannover, Germany

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  • Vivek Vikram Singh,

    Affiliation: Institute of Virology, Hannover Medical School, Hannover, Germany

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  • Oliver Dittrich-Breiholz,

    Affiliation: Institute of Biochemistry, Hannover Medical School, Hannover, Germany

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  • Michael Kracht,

    Affiliation: Institute of Pharmacology, Justus-Liebig-Universität Giessen, Giessen, Germany

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  • Thomas F. Schulz mail

    schulz.thomas@mh-hannover.de

    Affiliation: Institute of Virology, Hannover Medical School, Hannover, Germany

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  • Published: September 27, 2012
  • DOI: 10.1371/journal.ppat.1002927

About the Authors

Kiran Bala, Raffaella Bosco, Silvia Gramolelli, Darya A. Haas, Semra Kati, Marcel Pietrek, Anika Hävemeier, Yuri Yakushko, Vivek Vikram Singh, Thomas F. Schulz
Institute of Virology, Hannover Medical School, Hannover, Germany
Oliver Dittrich-Breiholz
Institute of Biochemistry, Hannover Medical School, Hannover, Germany
Michael Kracht
Institute of Pharmacology, Justus-Liebig-Universität Giessen, Giessen, Germany

Corresponding Author

Email: schulz.thomas@mh-hannover.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KB RB SG DAH SK MP AH YY VVS ODB TFS. Performed the experiments: KB RB SG DAH SK MP AH YY VVS ODB. Analyzed the data: KB RB SG DAH SK MP AH YY VVS ODB MK. Wrote the paper: KB TFS.