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Research Article

Loss of Effector and Anti-Inflammatory Natural Killer T Lymphocyte Function in Pathogenic Simian Immunodeficiency Virus Infection

  • Namita Rout,

    Affiliation: New England Primate Research Center, Harvard Medical School, Southborough, Massachusetts, United States of America

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  • Justin Greene,

    Affiliation: Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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  • Simon Yue,

    Affiliation: Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America

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  • David O'Connor,

    Affiliation: Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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  • R. Paul Johnson,

    Affiliation: New England Primate Research Center, Harvard Medical School, Southborough, Massachusetts, United States of America

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  • James G. Else,

    Affiliation: Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America

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  • Mark A. Exley,

    Affiliation: Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Amitinder Kaur mail

    amitinder_kaur@hms.harvard.edu

    Affiliation: New England Primate Research Center, Harvard Medical School, Southborough, Massachusetts, United States of America

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  • Published: September 20, 2012
  • DOI: 10.1371/journal.ppat.1002928

About the Authors

Namita Rout, R. Paul Johnson, Amitinder Kaur
New England Primate Research Center, Harvard Medical School, Southborough, Massachusetts, United States of America
Justin Greene, David O'Connor
Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
Simon Yue, Mark A. Exley
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
James G. Else
Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America

Corresponding Author

Email: amitinder_kaur@hms.harvard.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NR MAE AK. Performed the experiments: NR. Analyzed the data: NR AK. Contributed reagents/materials/analysis tools: JG SY DO RPJ JGE MAE. Wrote the paper: NR AK.