Advertisement
Research Article

Binding of Glycoprotein Srr1 of Streptococcus agalactiae to Fibrinogen Promotes Attachment to Brain Endothelium and the Development of Meningitis

  • Ho Seong Seo,

    Affiliation: Division of Infectious Diseases, Veterans Affairs Medical Center and the University of California, San Francisco, California, United States of America

    X
  • Rong Mu,

    Affiliation: Department of Biology and Center for Microbial Sciences, San Diego State University, San Diego, California, United States of America

    X
  • Brandon J. Kim,

    Affiliation: Department of Biology and Center for Microbial Sciences, San Diego State University, San Diego, California, United States of America

    X
  • Kelly S. Doran,

    Affiliations: Department of Biology and Center for Microbial Sciences, San Diego State University, San Diego, California, United States of America, Department of Pediatrics, University of California at San Diego, School of Medicine, La Jolla, California, United States of America

    X
  • Paul M. Sullam mail

    paul.sullam@ucsf.edu

    Affiliation: Division of Infectious Diseases, Veterans Affairs Medical Center and the University of California, San Francisco, California, United States of America

    X
  • Published: October 04, 2012
  • DOI: 10.1371/journal.ppat.1002947

About the Authors

Ho Seong Seo, Paul M. Sullam
Division of Infectious Diseases, Veterans Affairs Medical Center and the University of California, San Francisco, California, United States of America
Rong Mu, Brandon J. Kim, Kelly S. Doran
Department of Biology and Center for Microbial Sciences, San Diego State University, San Diego, California, United States of America
Kelly S. Doran
Department of Pediatrics, University of California at San Diego, School of Medicine, La Jolla, California, United States of America

Corresponding Author

Email: paul.sullam@ucsf.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HSS RM BJK KSD PMS. Performed the experiments: HSS RM BJK. Analyzed the data: HSS RM BJK KSD PMS. Contributed reagents/materials/analysis tools: HSS KSD PMS. Wrote the paper: HSS KSD PMS.