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Research Article

Evolutionary History and Attenuation of Myxoma Virus on Two Continents

  • Peter J. Kerr,

    Affiliation: CSIRO Ecosystem Sciences, Canberra, Australian Capital Territory, Australia

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  • Elodie Ghedin,

    Affiliation: Center for Vaccine Research, Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

    X
  • Jay V. DePasse,

    Affiliation: Center for Vaccine Research, Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

    X
  • Adam Fitch,

    Affiliation: Center for Vaccine Research, Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

    X
  • Isabella M. Cattadori,

    Affiliation: Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America

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  • Peter J. Hudson,

    Affiliation: Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America

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  • David C. Tscharke,

    Affiliation: Research School of Biology, The Australian National University, Canberra, Australian Capital Territory, Australia

    X
  • Andrew F. Read,

    Affiliations: Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America, Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Edward C. Holmes mail

    ech15@psu.edu

    Affiliations: Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America, Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Published: October 04, 2012
  • DOI: 10.1371/journal.ppat.1002950

About the Authors

Peter J. Kerr
CSIRO Ecosystem Sciences, Canberra, Australian Capital Territory, Australia
Elodie Ghedin, Jay V. DePasse, Adam Fitch
Center for Vaccine Research, Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
Isabella M. Cattadori, Peter J. Hudson, Andrew F. Read, Edward C. Holmes
Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America
David C. Tscharke
Research School of Biology, The Australian National University, Canberra, Australian Capital Territory, Australia
Andrew F. Read, Edward C. Holmes
Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America

Corresponding Author

Email: ech15@psu.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PJK EG IMC PJH AFR ECH. Performed the experiments: PJK EG JVD AF. Analyzed the data: PJK EG JVD AF ECH. Contributed reagents/materials/analysis tools: PJK EG JVD AF DCT. Wrote the paper: PJK EG IMC PJH DCT AFR ECH.