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Research Article

A Tail-like Assembly at the Portal Vertex in Intact Herpes Simplex Type-1 Virions

  • Michael F. Schmid,

    Affiliation: National Center for Macromolecular Imaging, Verna and Marrs Mclean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, United States of America

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  • Corey W. Hecksel,

    Affiliations: National Center for Macromolecular Imaging, Verna and Marrs Mclean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, United States of America, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, United States of America

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  • Ryan H. Rochat,

    Affiliations: National Center for Macromolecular Imaging, Verna and Marrs Mclean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, United States of America, Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas, United States of America

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  • David Bhella,

    Affiliation: MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom

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  • Wah Chiu mail,

    wah@bcm.edu

    Affiliations: National Center for Macromolecular Imaging, Verna and Marrs Mclean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, United States of America, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, United States of America, Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas, United States of America

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  • Frazer J. Rixon

    Affiliation: MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom

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  • Published: October 04, 2012
  • DOI: 10.1371/journal.ppat.1002961

About the Authors

Michael F. Schmid, Corey W. Hecksel, Ryan H. Rochat, Wah Chiu
National Center for Macromolecular Imaging, Verna and Marrs Mclean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, United States of America
Corey W. Hecksel, Wah Chiu
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, United States of America
Ryan H. Rochat, Wah Chiu
Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas, United States of America
David Bhella, Frazer J. Rixon
MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom

Corresponding Author

Email: wah@bcm.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MFS CWH RHR DB WC FJR. Performed the experiments: MFS CWH RHR DB WC FJR. Analyzed the data: MFS CWH RHR DB WC FJR. Contributed reagents/materials/analysis tools: MFS CWH RHR DB WC FJR. Wrote the paper: MFS CWH RHR DB WC FJR.