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Research Article

Prion Pathogenesis Is Faithfully Reproduced in Cerebellar Organotypic Slice Cultures

  • Jeppe Falsig,

    Affiliation: Institute of Neuropathology, Zürich, Switzerland

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  • Tiziana Sonati,

    Affiliation: Institute of Neuropathology, Zürich, Switzerland

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  • Uli S. Herrmann,

    Affiliation: Institute of Neuropathology, Zürich, Switzerland

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  • Dino Saban,

    Affiliation: Institute of Neuropathology, Zürich, Switzerland

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  • Bei Li,

    Affiliation: Institute of Neuropathology, Zürich, Switzerland

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  • Karina Arroyo,

    Affiliation: Institute of Neuropathology, Zürich, Switzerland

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  • Boris Ballmer,

    Affiliation: Institute of Neuropathology, Zürich, Switzerland

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  • Pawel P. Liberski,

    Affiliation: Laboratory of Electron Microscopy and Neuropathology, Department of Molecular Pathology and Neuropathology, Medical University of Lodz, Lodz, Poland

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  • Adriano Aguzzi mail

    adriano.aguzzi@usz.ch

    Affiliation: Institute of Neuropathology, Zürich, Switzerland

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  • Published: November 01, 2012
  • DOI: 10.1371/journal.ppat.1002985

About the Authors

Jeppe Falsig, Tiziana Sonati, Uli S. Herrmann, Dino Saban, Bei Li, Karina Arroyo, Boris Ballmer, Adriano Aguzzi
Institute of Neuropathology, Zürich, Switzerland
Pawel P. Liberski
Laboratory of Electron Microscopy and Neuropathology, Department of Molecular Pathology and Neuropathology, Medical University of Lodz, Lodz, Poland

Corresponding Author

Email: adriano.aguzzi@usz.ch

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JF AA. Performed the experiments: JF KA TS DS BL USH BB PPL. Analyzed the data: JF TS DS BL USH PPL BB AA. Wrote the paper: JF AA.