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Research Article

The Capping Domain in RalF Regulates Effector Functions

  • Eric Alix mail,

    eric.alix@yale.edu

    Affiliation: Department of Microbial Pathogenesis, Yale University School of Medicine, Boyer Center for Molecular Medicine, New Haven, Connecticut, United States of America

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  • Laurent Chesnel,

    Affiliation: Department of Microbial Pathogenesis, Yale University School of Medicine, Boyer Center for Molecular Medicine, New Haven, Connecticut, United States of America

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  • Brad J. Bowzard,

    Affiliation: Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, United States of America

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  • Aimee M. Tucker,

    Affiliation: Department of Microbiology and Immunology, University of South Alabama, Mobile, Alabama, United States of America

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  • Anna Delprato,

    Affiliation: Laboratoire d'Enzymologie et Biochimie Structurales, Centre de Recherche de Gif, CNRS Bat 34, CNRS, Gif sur Yvette, France

    Current address: BioScience Project, Wakefield, Massachusetts, United States of America.

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  • Jacqueline Cherfils,

    Affiliation: Laboratoire d'Enzymologie et Biochimie Structurales, Centre de Recherche de Gif, CNRS Bat 34, CNRS, Gif sur Yvette, France

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  • David O. Wood,

    Affiliation: Department of Microbiology and Immunology, University of South Alabama, Mobile, Alabama, United States of America

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  • Richard A. Kahn,

    Affiliation: Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, United States of America

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  • Craig R. Roy

    Affiliation: Department of Microbial Pathogenesis, Yale University School of Medicine, Boyer Center for Molecular Medicine, New Haven, Connecticut, United States of America

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  • Published: November 15, 2012
  • DOI: 10.1371/journal.ppat.1003012

About the Authors

Eric Alix, Laurent Chesnel, Craig R. Roy
Department of Microbial Pathogenesis, Yale University School of Medicine, Boyer Center for Molecular Medicine, New Haven, Connecticut, United States of America
Brad J. Bowzard, Richard A. Kahn
Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, United States of America
Aimee M. Tucker, David O. Wood
Department of Microbiology and Immunology, University of South Alabama, Mobile, Alabama, United States of America
Anna Delprato, Jacqueline Cherfils
Laboratoire d'Enzymologie et Biochimie Structurales, Centre de Recherche de Gif, CNRS Bat 34, CNRS, Gif sur Yvette, France

Corresponding Author

Email: eric.alix@yale.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EA LC BJB AMT AD JC DOW RAK CRR. Performed the experiments: EA LC BJB AMT AD. Analyzed the data: EA LC AD JC CRR. Contributed reagents/materials/analysis tools: EA LC BJB AMT AD. Wrote the paper: EA CRR.