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Research Article

Bromodomain Protein Brd4 Plays a Key Role in Merkel Cell Polyomavirus DNA Replication

  • Xin Wang,

    Affiliation: Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Jing Li,

    Affiliation: Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Rachel M. Schowalter,

    Affiliation: Tumor Virus Molecular Biology Section, Laboratory of Cellular Oncology, National Cancer Institute, Bethesda, Maryland, United States of America

    X
  • Jing Jiao,

    Affiliation: Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Christopher B. Buck,

    Affiliation: Tumor Virus Molecular Biology Section, Laboratory of Cellular Oncology, National Cancer Institute, Bethesda, Maryland, United States of America

    X
  • Jianxin You mail

    jianyou@mail.med.upenn.edu

    Affiliation: Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Published: November 08, 2012
  • DOI: 10.1371/journal.ppat.1003021

About the Authors

Xin Wang, Jing Li, Jing Jiao, Jianxin You
Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America
Rachel M. Schowalter, Christopher B. Buck
Tumor Virus Molecular Biology Section, Laboratory of Cellular Oncology, National Cancer Institute, Bethesda, Maryland, United States of America

Corresponding Author

Email: jianyou@mail.med.upenn.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: XW JL RMS CBB JY. Performed the experiments: XW JL RMS JJ. Analyzed the data: XW JL RMS JJ. Contributed reagents/materials/analysis tools: RMS CBB. Wrote the paper: XW RMS CBB JY.