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Research Article

Molecular Anatomy and Number of Antigen Specific CD8 T Cells Required to Cause Type 1 Diabetes

  • Michael B. A. Oldstone mail,

    mbaobo@scripps.edu

    Affiliation: Viral-Immunobiology Laboratory, Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

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  • Kurt H. Edelmann,
  • Dorian B. McGavern,
  • Justin T. Cruite,
  • Megan J. Welch
  • Published: November 29, 2012
  • DOI: 10.1371/journal.ppat.1003044

About the Authors

Michael B. A. Oldstone
Viral-Immunobiology Laboratory, Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

Corresponding Author

Email: mbaobo@scripps.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MBAO DBM KHE. Performed the experiments: KHE DBM JTC MJW. Analyzed the data: MBAO KHE DBM MJW. Contributed reagents/materials/analysis tools: MBAO DBM. Wrote the paper: MBAO.