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Research Article

Attenuated Salmonella Typhimurium Lacking the Pathogenicity Island-2 Type 3 Secretion System Grow to High Bacterial Numbers inside Phagocytes in Mice

  • Andrew J. Grant mail,

    ajg60@cam.ac.uk

    Affiliation: Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

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  • Fiona J. E. Morgan,

    Affiliation: Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

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  • Trevelyan J. McKinley,

    Affiliation: Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

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  • Gemma L. Foster,

    Affiliation: Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

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  • Duncan J. Maskell ,

    Affiliation: Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

    These authors are joint senior authors on this work.

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  • Pietro Mastroeni

    Affiliation: Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

    These authors are joint senior authors on this work.

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  • Published: December 06, 2012
  • DOI: 10.1371/journal.ppat.1003070

About the Authors

Andrew J. Grant, Fiona J. E. Morgan, Trevelyan J. McKinley, Gemma L. Foster, Duncan J. Maskell, Pietro Mastroeni
Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

Corresponding Author

Email: ajg60@cam.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AJG DJM PM. Performed the experiments: AJG FJEM GLF PM. Analyzed the data: AJG TJM DJM PM. Wrote the paper: AJG DJM PM. Obtained the funding: AJG DJM PM.