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Research Article

Fine Tuning Inflammation at the Front Door: Macrophage Complement Receptor 3-mediates Phagocytosis and Immune Suppression for Francisella tularensis

  • Shipan Dai equal contributor,

    equal contributor Contributed equally to this work with: Shipan Dai, Murugesan V. S. Rajaram

    Affiliation: Center for Microbial Interface Biology, Department of Microbial Infection and Immunity, The Ohio State University, Columbus, Ohio, United States of America

    X
  • Murugesan V. S. Rajaram equal contributor,

    equal contributor Contributed equally to this work with: Shipan Dai, Murugesan V. S. Rajaram

    Affiliation: Center for Microbial Interface Biology, Department of Microbial Infection and Immunity, The Ohio State University, Columbus, Ohio, United States of America

    X
  • Heather M. Curry,

    Affiliation: Center for Microbial Interface Biology, Department of Microbial Infection and Immunity, The Ohio State University, Columbus, Ohio, United States of America

    X
  • Rachel Leander,

    Affiliation: Mathematical Biosciences Institute, The Ohio State University, Columbus, Ohio, United States of America

    X
  • Larry S. Schlesinger mail

    larry.schlesinger@osumc.edu

    Affiliation: Center for Microbial Interface Biology, Department of Microbial Infection and Immunity, The Ohio State University, Columbus, Ohio, United States of America

    X
  • Published: January 24, 2013
  • DOI: 10.1371/journal.ppat.1003114

About the Authors

Shipan Dai, Murugesan V. S. Rajaram, Heather M. Curry, Larry S. Schlesinger
Center for Microbial Interface Biology, Department of Microbial Infection and Immunity, The Ohio State University, Columbus, Ohio, United States of America
Rachel Leander
Mathematical Biosciences Institute, The Ohio State University, Columbus, Ohio, United States of America

Corresponding Author

Email: larry.schlesinger@osumc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LSS SD MVSR. Performed the experiments: SD HMC MVSR. Analyzed the data: LSS SD RL MVSR. Wrote the paper: SD LSS HMC RL MVSR.