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Research Article

Assembly of the Type II Secretion System such as Found in Vibrio cholerae Depends on the Novel Pilotin AspS

  • Rhys A. Dunstan,

    Affiliation: Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Australia

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  • Eva Heinz,

    Affiliations: Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Australia, Victorian Bioinformatics Consortium, Monash University, Melbourne, Australia

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  • Lakshmi C. Wijeyewickrema,

    Affiliation: Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Australia

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  • Robert N. Pike,

    Affiliation: Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Australia

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  • Anthony W. Purcell,

    Affiliation: Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Australia

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  • Timothy J. Evans,

    Affiliation: Department of Molecular and Cellular Biochemistry and Center for Structural Biology, University of Kentucky, Lexington, Kentucky, United States of America

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  • Judyta Praszkier,

    Affiliations: Department of Microbiology and Immunology, The University of Melbourne, Melbourne, Australia, Monash Institute of Medical Research, Melbourne, Australia

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  • Roy M. Robins-Browne,

    Affiliations: Department of Microbiology and Immunology, The University of Melbourne, Melbourne, Australia, Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Australia

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  • Richard A. Strugnell,

    Affiliation: Department of Microbiology and Immunology, The University of Melbourne, Melbourne, Australia

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  • Konstantin V. Korotkov mail,

    kkorotkov@uky.edu (KVK); trevor.lithgow@monash.edu (TL)

    Affiliation: Department of Molecular and Cellular Biochemistry and Center for Structural Biology, University of Kentucky, Lexington, Kentucky, United States of America

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  • Trevor Lithgow mail

    kkorotkov@uky.edu (KVK); trevor.lithgow@monash.edu (TL)

    Affiliation: Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Australia

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  • Published: January 10, 2013
  • DOI: 10.1371/journal.ppat.1003117

About the Authors

Rhys A. Dunstan, Eva Heinz, Lakshmi C. Wijeyewickrema, Robert N. Pike, Anthony W. Purcell, Trevor Lithgow
Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Australia
Eva Heinz
Victorian Bioinformatics Consortium, Monash University, Melbourne, Australia
Timothy J. Evans, Konstantin V. Korotkov
Department of Molecular and Cellular Biochemistry and Center for Structural Biology, University of Kentucky, Lexington, Kentucky, United States of America
Judyta Praszkier, Roy M. Robins-Browne, Richard A. Strugnell
Department of Microbiology and Immunology, The University of Melbourne, Melbourne, Australia
Judyta Praszkier
Monash Institute of Medical Research, Melbourne, Australia
Roy M. Robins-Browne
Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Australia

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KVK TL. Performed the experiments: RAD EH LCW TJE JP. Analyzed the data: RNP AWP RMRB RAS KVK TL. Wrote the paper: RAD EH KVK TL.