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Research Article

Adaptive Immunity Alters Distinct Host Feeding Pathways during Nematode Induced Inflammation, a Novel Mechanism in Parasite Expulsion

  • John J. Worthington mail,

    john.worthington@manchester.ac.uk

    Affiliation: Manchester Immunology Group, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom

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  • Linda C. Samuelson,

    Affiliation: Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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  • Richard K. Grencis,

    Affiliation: Manchester Immunology Group, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom

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  • John T. McLaughlin

    Affiliation: School of Translational Medicine, School of Medicine, University of Manchester, Manchester, United Kingdom

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  • Published: January 17, 2013
  • DOI: 10.1371/journal.ppat.1003122

About the Authors

John J. Worthington, Richard K. Grencis
Manchester Immunology Group, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
Linda C. Samuelson
Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
John T. McLaughlin
School of Translational Medicine, School of Medicine, University of Manchester, Manchester, United Kingdom

Corresponding Author

Email: john.worthington@manchester.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JJW RKG JTM. Performed the experiments: JJW. Analyzed the data: JJW. Contributed reagents/materials/analysis tools: LCS. Wrote the paper: JJW LCS RKG JTM.