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Research Article

Atomic Model of Rabbit Hemorrhagic Disease Virus by Cryo-Electron Microscopy and Crystallography

  • Xue Wang equal contributor,

    equal contributor Contributed equally to this work with: Xue Wang, Fengting Xu, Jiasen Liu

    Affiliations: National Laboratory of Biomacromolecules, Institute of Biophysics (IBP), Chinese Academy of Sciences (CAS), Beijing, China, University of Chinese Academy of Sciences, Beijing, China

    X
  • Fengting Xu equal contributor,

    equal contributor Contributed equally to this work with: Xue Wang, Fengting Xu, Jiasen Liu

    Affiliation: Department of Biochemistry and Molecular Biology, College of Life Sciences, Beijing Normal University, Beijing, China

    X
  • Jiasen Liu equal contributor,

    equal contributor Contributed equally to this work with: Xue Wang, Fengting Xu, Jiasen Liu

    Affiliation: State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Science, Harbin, China

    X
  • Bingquan Gao,

    Affiliations: National Laboratory of Biomacromolecules, Institute of Biophysics (IBP), Chinese Academy of Sciences (CAS), Beijing, China, University of Chinese Academy of Sciences, Beijing, China

    X
  • Yanxin Liu,

    Affiliation: Beckman Institute and Department of Physics, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America

    X
  • Yujia Zhai,

    Affiliation: National Laboratory of Biomacromolecules, Institute of Biophysics (IBP), Chinese Academy of Sciences (CAS), Beijing, China

    X
  • Jun Ma,

    Affiliations: National Laboratory of Biomacromolecules, Institute of Biophysics (IBP), Chinese Academy of Sciences (CAS), Beijing, China, University of Chinese Academy of Sciences, Beijing, China

    X
  • Kai Zhang,

    Affiliations: National Laboratory of Biomacromolecules, Institute of Biophysics (IBP), Chinese Academy of Sciences (CAS), Beijing, China, University of Chinese Academy of Sciences, Beijing, China

    X
  • Timothy S. Baker,

    Affiliation: Department of Chemistry and Biochemistry and Division of Biological Sciences, University of California-San Diego, La Jolla, California, United States of America

    X
  • Klaus Schulten,

    Affiliation: Beckman Institute and Department of Physics, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America

    X
  • Dong Zheng mail,

    zhengd@bnu.edu.cn (DZ); pangh@xtal.tsinghua.edu.cn (HP); feisun@ibp.ac.cn (FS)

    Affiliation: Analytical and Testing Center, Beijing Normal University, Beijing, China

    X
  • Hai Pang mail,

    zhengd@bnu.edu.cn (DZ); pangh@xtal.tsinghua.edu.cn (HP); feisun@ibp.ac.cn (FS)

    Affiliation: School of Medicine, Tsinghua University, Beijing, China

    X
  • Fei Sun mail

    zhengd@bnu.edu.cn (DZ); pangh@xtal.tsinghua.edu.cn (HP); feisun@ibp.ac.cn (FS)

    Affiliation: National Laboratory of Biomacromolecules, Institute of Biophysics (IBP), Chinese Academy of Sciences (CAS), Beijing, China

    X
  • Published: January 17, 2013
  • DOI: 10.1371/journal.ppat.1003132

About the Authors

Xue Wang, Bingquan Gao, Yujia Zhai, Jun Ma, Kai Zhang, Fei Sun
National Laboratory of Biomacromolecules, Institute of Biophysics (IBP), Chinese Academy of Sciences (CAS), Beijing, China
Xue Wang, Bingquan Gao, Jun Ma, Kai Zhang
University of Chinese Academy of Sciences, Beijing, China
Fengting Xu
Department of Biochemistry and Molecular Biology, College of Life Sciences, Beijing Normal University, Beijing, China
Jiasen Liu
State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Science, Harbin, China
Yanxin Liu, Klaus Schulten
Beckman Institute and Department of Physics, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America
Timothy S. Baker
Department of Chemistry and Biochemistry and Division of Biological Sciences, University of California-San Diego, La Jolla, California, United States of America
Dong Zheng
Analytical and Testing Center, Beijing Normal University, Beijing, China
Hai Pang
School of Medicine, Tsinghua University, Beijing, China

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DZ HP FS. Performed the experiments: XW FX JL BG YL YZ JM KZ. Analyzed the data: XW HP FS. Wrote the paper: FS HP TSB YL KS.