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Research Article

Convergence and Divergence in the Evolution of the APOBEC3G-Vif Interaction Reveal Ancient Origins of Simian Immunodeficiency Viruses

  • Alex A. Compton,

    Affiliations: Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, Washington, United States of America, Divisions of Human Biology and Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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  • Michael Emerman mail

    memerman@fhcrc.org

    Affiliation: Divisions of Human Biology and Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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  • Published: January 24, 2013
  • DOI: 10.1371/journal.ppat.1003135

About the Authors

Alex A. Compton
Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, Washington, United States of America
Alex A. Compton, Michael Emerman
Divisions of Human Biology and Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

Corresponding Author

Email: memerman@fhcrc.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AAC ME. Performed the experiments: AAC. Analyzed the data: AAC ME. Contributed reagents/materials/analysis tools: AAC. Wrote the paper: AAC ME.