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Research Article

Novel Marmoset (Callithrix jacchus) Model of Human Herpesvirus 6A and 6B Infections: Immunologic, Virologic and Radiologic Characterization

  • Emily Leibovitch equal contributor,

    equal contributor Contributed equally to this work with: Emily Leibovitch, Jillian E. Wohler

    Affiliations: Viral Immunology Section, Neuroimmunology Branch, NINDS/NIH, Bethesda, Maryland, United States of America, Institute for Biomedical Sciences, George Washington University, Washington, DC, United States of America

    X
  • Jillian E. Wohler equal contributor,

    equal contributor Contributed equally to this work with: Emily Leibovitch, Jillian E. Wohler

    Affiliation: Viral Immunology Section, Neuroimmunology Branch, NINDS/NIH, Bethesda, Maryland, United States of America

    X
  • Sheila M. Cummings Macri,

    Affiliation: New England Primate Research Center, Harvard Medical School, Southborough, Massachusetts, United States of America

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  • Kelsey Motanic,

    Affiliation: Viral Immunology Section, Neuroimmunology Branch, NINDS/NIH, Bethesda, Maryland, United States of America

    X
  • Erin Harberts,

    Affiliation: Viral Immunology Section, Neuroimmunology Branch, NINDS/NIH, Bethesda, Maryland, United States of America

    X
  • María I. Gaitán,

    Affiliation: Translational Neuroradiology Unit, Neuroimmunology Branch, NINDS/NIH, Bethesda, Maryland, United States of America

    X
  • Pietro Maggi,

    Affiliation: Translational Neuroradiology Unit, Neuroimmunology Branch, NINDS/NIH, Bethesda, Maryland, United States of America

    X
  • Mary Ellis,

    Affiliation: New England Primate Research Center, Harvard Medical School, Southborough, Massachusetts, United States of America

    X
  • Susan Westmoreland,

    Affiliation: New England Primate Research Center, Harvard Medical School, Southborough, Massachusetts, United States of America

    X
  • Afonso Silva,

    Affiliation: Cerebral Microcirculation Unit, Laboratory of Functional and Molecular Imaging, NINDS/NIH, Bethesda, Maryland, United States of America

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  • Daniel S. Reich,

    Affiliation: Translational Neuroradiology Unit, Neuroimmunology Branch, NINDS/NIH, Bethesda, Maryland, United States of America

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  • Steven Jacobson mail

    jacobsons@ninds.nih.gov

    Affiliation: Viral Immunology Section, Neuroimmunology Branch, NINDS/NIH, Bethesda, Maryland, United States of America

    X
  • Published: January 31, 2013
  • DOI: 10.1371/journal.ppat.1003138

About the Authors

Emily Leibovitch, Jillian E. Wohler, Kelsey Motanic, Erin Harberts, Steven Jacobson
Viral Immunology Section, Neuroimmunology Branch, NINDS/NIH, Bethesda, Maryland, United States of America
Emily Leibovitch
Institute for Biomedical Sciences, George Washington University, Washington, DC, United States of America
Sheila M. Cummings Macri, Mary Ellis, Susan Westmoreland
New England Primate Research Center, Harvard Medical School, Southborough, Massachusetts, United States of America
María I. Gaitán, Pietro Maggi, Daniel S. Reich
Translational Neuroradiology Unit, Neuroimmunology Branch, NINDS/NIH, Bethesda, Maryland, United States of America
Afonso Silva
Cerebral Microcirculation Unit, Laboratory of Functional and Molecular Imaging, NINDS/NIH, Bethesda, Maryland, United States of America

Corresponding Author

Email: jacobsons@ninds.nih.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EL JEW SJ. Performed the experiments: EL SJ SMCM KM EH MIG PM ME. Analyzed the data: EL JEW SMCM AS SW DSR SJ. Wrote the paper: EL JEW SMCM MIG DSR SJ.