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Research Article

IL-17 Mediates Immunopathology in the Absence of IL-10 Following Leishmania major Infection

  • Claudia Gonzalez-Lombana,

    Affiliation: Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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  • Ciara Gimblet,

    Affiliation: Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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  • Olivia Bacellar,

    Affiliation: Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais-INCT-DT(CNPq/MCT), Serviço de Imunologia, Hospital Universitario Prof. Edgard Santos, Universidade Federal da Bahia Salvador, Bahia, Brasil

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  • Walker W. Oliveira,

    Affiliation: Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais-INCT-DT(CNPq/MCT), Serviço de Imunologia, Hospital Universitario Prof. Edgard Santos, Universidade Federal da Bahia Salvador, Bahia, Brasil

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  • Sara Passos,

    Affiliation: Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais-INCT-DT(CNPq/MCT), Serviço de Imunologia, Hospital Universitario Prof. Edgard Santos, Universidade Federal da Bahia Salvador, Bahia, Brasil

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  • Lucas P. Carvalho,

    Affiliation: Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais-INCT-DT(CNPq/MCT), Serviço de Imunologia, Hospital Universitario Prof. Edgard Santos, Universidade Federal da Bahia Salvador, Bahia, Brasil

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  • Michael Goldschmidt,

    Affiliation: Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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  • Edgar M. Carvalho,

    Affiliation: Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais-INCT-DT(CNPq/MCT), Serviço de Imunologia, Hospital Universitario Prof. Edgard Santos, Universidade Federal da Bahia Salvador, Bahia, Brasil

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  • Phillip Scott mail

    pscott@vet.upenn.edu

    Affiliation: Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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  • Published: March 21, 2013
  • DOI: 10.1371/journal.ppat.1003243

About the Authors

Claudia Gonzalez-Lombana, Ciara Gimblet, Michael Goldschmidt, Phillip Scott
Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
Olivia Bacellar, Walker W. Oliveira, Sara Passos, Lucas P. Carvalho, Edgar M. Carvalho
Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais-INCT-DT(CNPq/MCT), Serviço de Imunologia, Hospital Universitario Prof. Edgard Santos, Universidade Federal da Bahia Salvador, Bahia, Brasil

Corresponding Author

Email: pscott@vet.upenn.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Reviewed manuscript: CG WWO OB SP LPC EMC MG. Conceived and designed the experiments: CGL PS OB WWO SP LPC EMC. Performed the experiments: CGL CG WWO. Analyzed the data: CGL CG PS WWO OB SP LPC EMC MG. Contributed reagents/materials/analysis tools: PS OB SP LPC EMC. Wrote the paper: CGL PS.