Advertisement
Research Article

Murinization of Internalin Extends Its Receptor Repertoire, Altering Listeria monocytogenes Cell Tropism and Host Responses

  • Yu-Huan Tsai,

    Affiliations: Institut Pasteur, Biology of Infection Unit, Paris, France, Inserm U1117, Paris, France, Université Paris Diderot, Sorbonne Paris Cité, Paris, France

    X
  • Olivier Disson,

    Affiliations: Institut Pasteur, Biology of Infection Unit, Paris, France, Inserm U1117, Paris, France

    X
  • Hélène Bierne,

    Affiliations: Institut Pasteur, Unité des Interactions Bactéries Cellules, Paris, France, Inserm, U604, Paris, France, INRA, USC2020, Paris, France

    X
  • Marc Lecuit mail

    marc.lecuit@pasteur.fr

    Affiliations: Institut Pasteur, Biology of Infection Unit, Paris, France, Inserm U1117, Paris, France, Institut Pasteur, French National Reference Center and World Health Organization Collaborating Center on Listeria, Paris, France, Université Paris Descartes, Sorbonne Paris Cité, Institut Imagine, Paris, France, Necker-Enfants Malades University Hospital, APHP, Division of Infectious Diseases and Tropical Medicine, Paris, France

    X
  • Published: May 30, 2013
  • DOI: 10.1371/journal.ppat.1003381

About the Authors

Yu-Huan Tsai, Olivier Disson, Marc Lecuit
Institut Pasteur, Biology of Infection Unit, Paris, France
Yu-Huan Tsai, Olivier Disson, Marc Lecuit
Inserm U1117, Paris, France
Yu-Huan Tsai
Université Paris Diderot, Sorbonne Paris Cité, Paris, France
Hélène Bierne
Institut Pasteur, Unité des Interactions Bactéries Cellules, Paris, France
Hélène Bierne
Inserm, U604, Paris, France
Hélène Bierne
INRA, USC2020, Paris, France
Marc Lecuit
Institut Pasteur, French National Reference Center and World Health Organization Collaborating Center on Listeria, Paris, France
Marc Lecuit
Université Paris Descartes, Sorbonne Paris Cité, Institut Imagine, Paris, France
Marc Lecuit
Necker-Enfants Malades University Hospital, APHP, Division of Infectious Diseases and Tropical Medicine, Paris, France

Corresponding Author

Email: marc.lecuit@pasteur.fr

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YHT OD HB ML. Performed the experiments: YHT OD HB. Analyzed the data: YHT OD HB ML. Wrote the paper: YHT OD HB ML.