Advertisement
Research Article

Cytotoxic T Cells Mediate Pathology and Metastasis in Cutaneous Leishmaniasis

  • Fernanda O. Novais,

    Affiliation: Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Lucas P. Carvalho,

    Affiliation: Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais-INCT-DT(CNPq/MCT), Serviço de Imunologia, Hospital Universitario Prof. Edgard Santos, Universidade Federal da Bahia Salvador, Bahia, Brazil

    X
  • Joel W. Graff,

    Affiliation: Iowa City VA Medical Center, Iowa City, Iowa, United States of America

    X
  • Daniel P. Beiting,

    Affiliation: Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Gordon Ruthel,

    Affiliation: Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • David S. Roos,

    Affiliation: Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Michael R. Betts,

    Affiliation: Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Michael H. Goldschmidt,

    Affiliation: Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Mary E. Wilson,

    Affiliation: Iowa City VA Medical Center, Iowa City, Iowa, United States of America

    X
  • Camila I. de Oliveira,

    Affiliation: Centro de Pesquisas Gonçalo Moniz, Fundaçao Oswaldo Cruz, Salvador, Brazil

    X
  • Phillip Scott mail

    pscott@vet.upenn.edu

    Affiliation: Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Published: July 18, 2013
  • DOI: 10.1371/journal.ppat.1003504

About the Authors

Fernanda O. Novais, Gordon Ruthel, Michael H. Goldschmidt, Phillip Scott
Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
Lucas P. Carvalho
Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais-INCT-DT(CNPq/MCT), Serviço de Imunologia, Hospital Universitario Prof. Edgard Santos, Universidade Federal da Bahia Salvador, Bahia, Brazil
Joel W. Graff, Mary E. Wilson
Iowa City VA Medical Center, Iowa City, Iowa, United States of America
Daniel P. Beiting, David S. Roos
Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
Michael R. Betts
Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
Camila I. de Oliveira
Centro de Pesquisas Gonçalo Moniz, Fundaçao Oswaldo Cruz, Salvador, Brazil

Corresponding Author

Email: pscott@vet.upenn.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: FON LPC JWG DPB DSR MRB MEW CIO PS. Performed the experiments: FON LPC JWG DPB GR. Analyzed the data: FON DPB GR MHG MRB PS. Contributed reagents/materials/analysis tools: DSR MRB MEW. Wrote the paper: FON PS.