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Research Article

Caspase-1-Dependent and -Independent Cell Death Pathways in Burkholderia pseudomallei Infection of Macrophages

  • Antje Bast equal contributor,

    equal contributor Contributed equally to this work with: Antje Bast, Kathrin Krause

    Affiliation: Friedrich Loeffler Institute of Medical Microbiology, University Medicine Greifswald, Greifswald, Germany

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  • Kathrin Krause equal contributor,

    equal contributor Contributed equally to this work with: Antje Bast, Kathrin Krause

    Affiliation: Friedrich Loeffler Institute of Medical Microbiology, University Medicine Greifswald, Greifswald, Germany

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  • Imke H. E. Schmidt,

    Affiliation: Friedrich Loeffler Institute of Medical Microbiology, University Medicine Greifswald, Greifswald, Germany

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  • Matsayapan Pudla,

    Affiliations: Friedrich Loeffler Institute of Medical Microbiology, University Medicine Greifswald, Greifswald, Germany, Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand

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  • Stefanie Brakopp,

    Affiliation: Friedrich Loeffler Institute of Medical Microbiology, University Medicine Greifswald, Greifswald, Germany

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  • Verena Hopf,

    Affiliation: Friedrich Loeffler Institute of Medical Microbiology, University Medicine Greifswald, Greifswald, Germany

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  • Katrin Breitbach,

    Affiliation: Friedrich Loeffler Institute of Medical Microbiology, University Medicine Greifswald, Greifswald, Germany

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  • Ivo Steinmetz mail

    steinmetz.ivo@uni-greifswald.de

    Affiliation: Friedrich Loeffler Institute of Medical Microbiology, University Medicine Greifswald, Greifswald, Germany

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  • Published: March 13, 2014
  • DOI: 10.1371/journal.ppat.1003986

About the Authors

Antje Bast, Kathrin Krause, Imke H. E. Schmidt, Matsayapan Pudla, Stefanie Brakopp, Verena Hopf, Katrin Breitbach, Ivo Steinmetz
Friedrich Loeffler Institute of Medical Microbiology, University Medicine Greifswald, Greifswald, Germany
Matsayapan Pudla
Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand

Corresponding Author

Email: steinmetz.ivo@uni-greifswald.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AB KK IHES IS. Performed the experiments: AB KK IHES MP SB VH. Analyzed the data: AB KK IHES KB IS. Wrote the paper: AB KK IHES IS.