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Research Article

Eosinophils Are Important for Protection, Immunoregulation and Pathology during Infection with Nematode Microfilariae

  • Emma T. Cadman,

    Affiliation: The Royal Veterinary College, Department of Comparative Biomedical Sciences, London, United Kingdom

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  • Katherine A. Thysse,

    Affiliation: The Royal Veterinary College, Department of Comparative Biomedical Sciences, London, United Kingdom

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  • Siobhan Bearder,

    Affiliation: The Royal Veterinary College, Department of Comparative Biomedical Sciences, London, United Kingdom

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  • Anita Y. N. Cheung,

    Affiliation: The Royal Veterinary College, Department of Comparative Biomedical Sciences, London, United Kingdom

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  • Ashleigh C. Johnston,

    Affiliation: The Royal Veterinary College, Department of Comparative Biomedical Sciences, London, United Kingdom

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  • James J. Lee,

    Affiliation: Division of Pulmonary Medicine, Department of Biochemistry and Molecular Biology, Mayo Clinic Arizona, Scottsdale, Arizona, United States of America

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  • Rachel A. Lawrence mail

    rlawrence@rvc.ac.uk

    Affiliation: The Royal Veterinary College, Department of Comparative Biomedical Sciences, London, United Kingdom

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  • Published: March 13, 2014
  • DOI: 10.1371/journal.ppat.1003988

About the Authors

Emma T. Cadman, Katherine A. Thysse, Siobhan Bearder, Anita Y. N. Cheung, Ashleigh C. Johnston, Rachel A. Lawrence
The Royal Veterinary College, Department of Comparative Biomedical Sciences, London, United Kingdom
James J. Lee
Division of Pulmonary Medicine, Department of Biochemistry and Molecular Biology, Mayo Clinic Arizona, Scottsdale, Arizona, United States of America

Corresponding Author

Email: rlawrence@rvc.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ETC RAL. Performed the experiments: ETC KAT AYNC SB ACJ RAL. Analyzed the data: ETC KAT SB ACJ RAL. Contributed reagents/materials/analysis tools: JJL RAL. Wrote the paper: ETC RAL.