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Research Article

Neutralizing Antibody Fails to Impact the Course of Ebola Virus Infection in Monkeys

  • Wendelien B Oswald,

    Affiliation: Departments of Immunology and Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America

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  • Thomas W Geisbert,

    Affiliation: United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America

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  • Kelly J Davis,

    Affiliation: United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America

    ¤a Current address: Charles River Laboratories, Preclinical Services, Redfield, Arkansas, United States of America

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  • Joan B Geisbert,

    Affiliation: United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America

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  • Nancy J Sullivan,

    Affiliation: Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Peter B Jahrling,

    Affiliation: United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America

    ¤b Current address: Integrated Research Facility, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Paul W. H. I Parren,

    Affiliation: Departments of Immunology and Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America

    ¤c Current address: Genmab, Utrecht, The Netherlands

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  • Dennis R Burton mail

    To whom correspondence should be addressed. E-mail: burton@scripps.edu

    Affiliation: Departments of Immunology and Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America

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  • Published: January 19, 2007
  • DOI: 10.1371/journal.ppat.0030009

About the Authors

Wendelien B Oswald, Paul W. H. I Parren, Dennis R Burton
Departments of Immunology and Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America
Thomas W Geisbert, Kelly J Davis, Joan B Geisbert, Peter B Jahrling
United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America
Nancy J Sullivan
Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America

Corresponding Author

Email: burton@scripps.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

TWG, PBJ, PWHIP, and DRB conceived and designed the experiments. TWG, KJD, JBG, NJS, PBJ, and PWHIP performed the experiments. WBO, TWG, PBJ, PWHIP, and DRB analyzed the data. TWG, KJD, and NJS contributed reagents/materials/analysis tools. WBO and DRB wrote the paper.