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Table of Contents: September 2005

COVER

Bacterium in a sputum sample

Image Credit: Image courtesy of United States Centers for Disease Control and Prevention; cover image design by Sapna Khandwala.
Issue Image

In this issue, research by Gutierrez et al and by Jian et al gives important new insights into the origin and virulence of Mycobacterium tuberculosis, a major human pathogen. Shown here is the bacterium in a sputum sample which has been stained.

Editorial

Opinion

Research Articles

SIVsm Quasispecies Adaptation to a New Simian Host

Linda J Demma, John M Logsdon Jr., Thomas H Vanderford, Mark B Feinberg, Silvija I Staprans

Influenza Virus PB1-F2 Protein Induces Cell Death through Mitochondrial ANT3 and VDAC1

Dmitriy Zamarin, Adolfo García-Sastre, Xiaoyao Xiao, Rong Wang, Peter Palese

Inhibition of MHC Class I Is a Virulence Factor in Herpes Simplex Virus Infection of Mice

Mark T Orr, Kurt H Edelmann, Jeffrey Vieira, Lawrence Corey, David H Raulet, Christopher B Wilson

Vibrio cholerae Infection of Drosophila melanogaster Mimics the Human Disease Cholera

Nathan S Blow, Robert N Salomon, Kerry Garrity, Isabelle Reveillaud, Alan Kopin, F. Rob Jackson, Paula I Watnick

A Surface Groove Essential for Viral Bcl-2 Function During Chronic Infection In Vivo

Joy Loh, Qiulong Huang, Andrew M Petros, David Nettesheim, Linda F. van Dyk, Lucia Labrada, Samuel H Speck, Beth Levine, Edward T Olejniczak, Herbert W Virgin IV

Ancient Origin and Gene Mosaicism of the Progenitor of Mycobacterium tuberculosis

M. Cristina Gutierrez, Sylvain Brisse, Roland Brosch, Michel Fabre, Bahia Omaïs, Magali Marmiesse, Philip Supply, Veronique Vincent

Natural Variation in Vif: Differential Impact on APOBEC3G/3F and a Potential Role in HIV-1 Diversification

Viviana Simon, Veronique Zennou, Deya Murray, Yaoxing Huang, David D Ho, Paul D Bieniasz