Table of Contents: July 2007


Uropathogenic E. coli

Image Credit: Micrograph by Danelle Eto. Processed using a craquelure filter with Adobe Photoshop software.
Issue Image

Uropathogenic Escherichia coli (blue) expressing type 1 pili invade bladder epithelial cells by engaging α3β1 integrin receptors (green) and F-actin (red). Similar interactions may facilitate the uptake of other type 1–piliated bacterial pathogens in diverse niches throughout the host (see Eto et al, e100).


Research Articles

Molecular Basis of Resistance to Muramidase and Cationic Antimicrobial Peptide Activity of Lysozyme in Staphylococci

Silvia Herbert, Agnieszka Bera, Christiane Nerz, Dirk Kraus, Andreas Peschel, Christiane Goerke, Michael Meehl, Ambrose Cheung, Friedrich Götz

Regulated Degradation of the HIV-1 Vpu Protein through a βTrCP-Independent Pathway Limits the Release of Viral Particles

Emilie Estrabaud, Erwann Le Rouzic, Sandra Lopez-Vergès, Marina Morel, Nadia Belaïdouni, Richard Benarous, Catherine Transy, Clarisse Berlioz-Torrent, Florence Margottin-Goguet

Cell-Specific IRF-3 Responses Protect against West Nile Virus Infection by Interferon-Dependent and -Independent Mechanisms

Stephane Daffis, Melanie A Samuel, Brian C Keller, Michael Gale Jr., Michael S Diamond

A Very Late Viral Protein Triggers the Lytic Release of SV40

Robert Daniels, Dorota Sadowicz, Daniel N Hebert

Microfluidic Modeling of Cell−Cell Interactions in Malaria Pathogenesis

Meher Antia, Thurston Herricks, Pradipsinh K Rathod

Hepatitis C Virus p7 Protein Is Crucial for Assembly and Release of Infectious Virions

Eike Steinmann, Francois Penin, Stephanie Kallis, Arvind H Patel, Ralf Bartenschlager, Thomas Pietschmann

Mycobacterium tuberculosis nuoG Is a Virulence Gene That Inhibits Apoptosis of Infected Host Cells

Kamalakannan Velmurugan, Bing Chen, Jessica L Miller, Sharon Azogue, Serdar Gurses, Tsungda Hsu, Michael Glickman, William R Jacobs Jr., Steven A Porcelli, Volker Briken

HIV-1 Vpr-Mediated G2 Arrest Involves the DDB1-CUL4AVPRBP E3 Ubiquitin Ligase

Jean-Philippe Belzile, Ghislaine Duisit, Nicole Rougeau, Johanne Mercier, Andrés Finzi, Éric A Cohen

The OmpA-Like Protein Loa22 Is Essential for Leptospiral Virulence

Paula Ristow, Pascale Bourhy, Flávia Weykamp da Cruz McBride, Claudio Pereira Figueira, Michel Huerre, Patrick Ave, Isabelle Saint Girons, Albert I Ko, Mathieu Picardeau

Integrin-Mediated Host Cell Invasion by Type 1–Piliated Uropathogenic Escherichia coli

Danelle S Eto, Tiffani A Jones, Jamie L Sundsbak, Matthew A Mulvey

Oral Transmissibility of Prion Disease Is Enhanced by Binding to Soil Particles

Christopher J Johnson, Joel A Pedersen, Rick J Chappell, Debbie McKenzie, Judd M Aiken

Evidence of Differential HLA Class I-Mediated Viral Evolution in Functional and Accessory/Regulatory Genes of HIV-1

Zabrina L Brumme, Chanson J Brumme, David Heckerman, Bette T Korber, Marcus Daniels, Jonathan Carlson, Carl Kadie, Tanmoy Bhattacharya, Celia Chui, James Szinger, Theresa Mo, Robert S Hogg, Julio S. G Montaner, Nicole Frahm, Christian Brander, Bruce D Walker, P. Richard Harrigan

Plasmodium Strain Determines Dendritic Cell Function Essential for Survival from Malaria

Michelle N Wykes, Xue Q Liu, Lynette Beattie, Danielle I Stanisic, Katryn J Stacey, Mark J Smyth, Ranjeny Thomas, Michael F Good