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Table of Contents: October 2007

COVER

African trypanosomes

Image Credit: Image provided by Jared R. Helm and the University of Iowa Central Microscopy Research Facility.
Issue Image

Colorized scanning electron micrograph of African trypanosomes, which are transmitted by tsetse flies in Africa and cause human sleeping sickness. In the bloodstream, the trypanosomes evade the immune system by periodically switching their major surface protein. A trypanosome-encoded protease helps remove this protein when the trypanosomes are ingested by tsetse flies (See Grandgenett et al, e150.)

Opinion

Pathogenesis, Virulence, and Infective Dose

Paul Schmid-Hempel, Steven A Frank

Review

Research Articles

Target Cell APOBEC3C Can Induce Limited G-to-A Mutation in HIV-1

Khaoula Bourara, Teri J Liegler, Robert M Grant

RNAi Screen in Drosophila Cells Reveals the Involvement of the Tom Complex in Chlamydia Infection

Isabelle Derré, Marc Pypaert, Alice Dautry-Varsat, Hervé Agaisse

Evidence for Direct Involvement of the Capsid Protein in HIV Infection of Nondividing Cells

Masahiro Yamashita, Omar Perez, Thomas J Hope, Michael Emerman

Small-Molecule Inhibition of HIV pre-mRNA Splicing as a Novel Antiretroviral Therapy to Overcome Drug Resistance

Nadia Bakkour, Yea-Lih Lin, Sophie Maire, Lilia Ayadi, Florence Mahuteau-Betzer, Chi Hung Nguyen, Clément Mettling, Pierre Portales, David Grierson, Benoit Chabot, Philippe Jeanteur, Christiane Branlant, Pierre Corbeau, Jamal Tazi

A Virtual Look at Epstein–Barr Virus Infection: Biological Interpretations

Karen A Duca, Michael Shapiro, Edgar Delgado-Eckert, Vey Hadinoto, Abdul S Jarrah, Reinhard Laubenbacher, Kichol Lee, Katherine Luzuriaga, Nicholas F Polys, David A Thorley-Lawson

Genome Sequence of Babesia bovis and Comparative Analysis of Apicomplexan Hemoprotozoa

Kelly A Brayton, Audrey O. T Lau, David R Herndon, Linda Hannick, Lowell S Kappmeyer, Shawn J Berens, Shelby L Bidwell, Wendy C Brown, Jonathan Crabtree, Doug Fadrosh, Tamara Feldblum, Heather A Forberger, Brian J Haas, Jeanne M Howell, Hoda Khouri, Hean Koo, David J Mann, Junzo Norimine, Ian T Paulsen, Diana Radune, Qinghu Ren, Roger K Smith Jr., Carlos E Suarez, Owen White, Jennifer R Wortman, Donald P Knowles Jr., Terry F McElwain, Vishvanath M Nene

A Function for a Specific Zinc Metalloprotease of African Trypanosomes

Paul M Grandgenett, Keiko Otsu, Helen R Wilson, Mary E Wilson, John E Donelson

Influenza Virus Transmission Is Dependent on Relative Humidity and Temperature

Anice C Lowen, Samira Mubareka, John Steel, Peter Palese

Malaria Impairs T Cell Clustering and Immune Priming despite Normal Signal 1 from Dendritic Cells

Owain R Millington, Vivienne B Gibson, Catherine M Rush, Bernd H Zinselmeyer, R. Stephen Phillips, Paul Garside, James M Brewer

Human CD4+ T Cell Epitopes from Vaccinia Virus Induced by Vaccination or Infection

J. Mauricio Calvo-Calle, Iwona Strug, Maria-Dorothea Nastke, Stephen P Baker, Lawrence J Stern

HMBA Releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and Activates HIV Transcription

Xavier Contreras, Matjaz Barboric, Tina Lenasi, B. Matija Peterlin

Growth of H5N1 Influenza A Viruses in the Upper Respiratory Tracts of Mice

Masato Hatta, Yasuko Hatta, Jin Hyun Kim, Shinji Watanabe, Kyoko Shinya, Tung Nguyen, Phuong Song Lien, Quynh Mai Le, Yoshihiro Kawaoka

A Single Mutation in the PB1-F2 of H5N1 (HK/97) and 1918 Influenza A Viruses Contributes to Increased Virulence

Gina M Conenello, Dmitriy Zamarin, Lucy A Perrone, Terrence Tumpey, Peter Palese

A Viral Nanoparticle with Dual Function as an Anthrax Antitoxin and Vaccine

Darly J Manayani, Diane Thomas, Kelly A Dryden, Vijay Reddy, Marc E Siladi, John M Marlett, G. Jonah A Rainey, Michael E Pique, Heather M Scobie, Mark Yeager, John A. T Young, Marianne Manchester, Anette Schneemann

Correction

Correction: Synergy or Independence? Deciphering the Interaction of HLA Class I and NK Cell KIR Alleles in Early HIV-1 Disease Progression

Jason D Barbour, Uma Sriram, Stacy J Caillier, Jay A Levy, Frederick M Hecht, Jorge R Oksenberg