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Table of Contents: May 2006

COVER

Chlamydia recruits BAD protein

Image Credit: Photograph provided by David Ojcius.
Issue Image

Chlamydia trachomatis promotes survival of the infected host cell, allowing the bacteria to complete their infection cycle. Shown here are Chlamydia vacuoles (green) that have recruited the death-inducing protein BAD. When released from the vacuoles, BAD helps to initiate host-cell death (see Verbeke et al).

Opinion

Review

Crossing the Line: Selection and Evolution of Virulence Traits

Nat F Brown, Mark E Wickham, Brian K Coombes, B. Brett Finlay

Research Articles

Transcriptional Silencing of Multiple Genes in Trophozoites of Entamoeba histolytica

Rivka Bracha, Yael Nuchamowitz, Michael Anbar, David Mirelman

The Malarial Host-Targeting Signal Is Conserved in the Irish Potato Famine Pathogen

Souvik Bhattacharjee, N. Luisa Hiller, Konstantinos Liolios, Joe Win, Thirumala-Devi Kanneganti, Carolyn Young, Sophien Kamoun, Kasturi Haldar

Effective Control of Chronic γ-Herpesvirus Infection by Unconventional MHC Class Ia–Independent CD8 T Cells

Douglas C Braaten, James Scott McClellan, Ilhem Messaoudi, Scott A Tibbetts, Kelly B McClellan, Janko Nikolich-Zugich, Herbert W Virgin IV

Effect of DNA Repair Protein Rad18 on Viral Infection

Aliza G Lloyd, Satoshi Tateishi, Paul D Bieniasz, Mark A Muesing, Masaru Yamaizumi, Lubbertus C. F Mulder

The Tripartite Associations between Bacteriophage, Wolbachia, and Arthropods

Seth R Bordenstein, Michelle L Marshall, Adam J Fry, Ulandt Kim, Jennifer J Wernegreen

Recruitment of BAD by the Chlamydia trachomatis Vacuole Correlates with Host-Cell Survival

Philippe Verbeke, Lynn Welter-Stahl, Songmin Ying, Jon Hansen, Georg Häcker, Toni Darville, David M Ojcius

Legionella pneumophila Exploits PI(4)P to Anchor Secreted Effector Proteins to the Replicative Vacuole

Stefan S Weber, Curdin Ragaz, Katrin Reus, Yves Nyfeler, Hubert Hilbi