Table of Contents | June 2006

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Schistosome egg excretion

A female schistosome excreting an egg through the gonopore. The female schistosome resides in a ventral groove of the male, the gynecophoric canal. The male worm sends a stimulus to regulate female-specific gene expression that in turn controls female reproductive development and subsequent egg production. Osman et al demonstrate that host TGFα can send a signal that is transduced by the schistosome TGFα pathway to regulate the expression of a Gynecophoric Canal Protein that may play a role in worm pairing that is a prerequisite for the male to send a stimulus to the female worm.

Image Credit: Photo by Ahmed Osman.

Opinion

Shield as Signal: Lipopolysaccharides and the Evolution of Immunity to Gram-Negative Bacteria

Robert S Munford, Alan W Varley

Review

The Thymus Is a Common Target Organ in Infectious Diseases

Wilson Savino

Research Articles

Listeria monocytogenes Traffics from Maternal Organs to the Placenta and Back

Anna I Bakardjiev, Julie A Theriot, Daniel A Portnoy

Author Summary

A Systematic Map of Genetic Variation in Plasmodium falciparum

Claire Kidgell, Sarah K Volkman, Johanna Daily, Justin O Borevitz, David Plouffe, Yingyao Zhou, Jeffrey R Johnson, Karine G. Le Roch, Ousmane Sarr, Omar Ndir, Soulyemane Mboup, Serge Batalov, Dyann F Wirth, Elizabeth A Winzeler

Author Summary

Antibody-Independent Control of γ-Herpesvirus Latency via B Cell Induction of Anti-Viral T Cell Responses

Kelly B McClellan, Shivaprakash Gangappa, Samuel H Speck, Herbert W. Virgin IV

Author Summary

Host-Specific Response to HCV Infection in the Chimeric SCID-beige/Alb-uPA Mouse Model: Role of the Innate Antiviral Immune Response

Kathie-Anne Walters, Michael A Joyce, Jill C Thompson, Maria W Smith, Matthew M Yeh, Sean Proll, Lin-Fu Zhu, T. J Gao, Norman M Kneteman, D. Lorne Tyrrell, Michael G Katze

Author Summary

Retroviral DNA Integration: Viral and Cellular Determinants of Target-Site Selection

Mary K Lewinski, Masahiro Yamashita, Michael Emerman, Angela Ciuffi, Heather Marshall, Gregory Crawford, Francis Collins, Paul Shinn, Jeremy Leipzig, Sridhar Hannenhalli, Charles C Berry, Joseph R Ecker, Frederic D Bushman

Author Summary

Schistosoma mansoni TGF-β Receptor II: Role in Host Ligand-Induced Regulation of a Schistosome Target Gene

Ahmed Osman, Edward G Niles, Sergio Verjovski-Almeida, Philip T LoVerde

Author Summary

Impact of Bacterial Genetics on the Transmission of Isoniazid-Resistant Mycobacterium tuberculosis

Sebastien Gagneux, Marcos V Burgos, Kathryn DeRiemer, Antonio Enciso, Samira Muñoz, Phillip C Hopewell, Peter M Small, Alexander S Pym

Author Summary

CCR5 Is Essential for NK Cell Trafficking and Host Survival following Toxoplasma gondii Infection

Imtiaz A Khan, Seddon Y Thomas, Magali M Moretto, Frederick S Lee, Sabina A Islam, Crescent Combe, Joseph D Schwartzman, Andrew D Luster

Author Summary

Anopheles gambiae Immune Responses to Human and Rodent Plasmodium Parasite Species

Yuemei Dong, Ruth Aguilar, Zhiyong Xi, Emma Warr, Emmanuel Mongin, George Dimopoulos

Author Summary

Detrimental Contribution of the Toll-Like Receptor (TLR)3 to Influenza A Virus–Induced Acute Pneumonia

Ronan Le Goffic, Viviane Balloy, Micheline Lagranderie, Lena Alexopoulou, Nicolas Escriou, Richard Flavell, Michel Chignard, Mustapha Si-Tahar

Author Summary

Prevalence of Local Immune Response against Oral Infection in a Drosophila/Pseudomonas Infection Model

Peter Liehl, Mark Blight, Nicolas Vodovar, Frédéric Boccard, Bruno Lemaitre

Author Summary

Envelope Exchange for the Generation of Live-Attenuated Arenavirus Vaccines

Andreas Bergthaler, Nicolas U Gerber, Doron Merkler, Edit Horvath, Juan Carlos de la Torre, Daniel D Pinschewer

Author Summary

Correction

Correction: A New Bacillus anthracis Found in Wild Chimpanzees and a Gorilla from West and Central Africa

Fabian H Leendertz, Saniye Yumlu, Georg Pauli, Christophe Boesch, Emmanuel Couacy-Hymann, Linda Vigilant, Sandra Junglen, Svenja Schenk, Heinz Ellerbrok