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Visualization of four distinct influenza viral RNA segments within a single cell.

A 3D rendering generated using Imaris software (from Bitplane) of an MDCK cell infected with influenza A/WSN/1933 (H1N1) virus with four influenza viral RNA segments identified by fluorescent in situ hybridization: PB2 (red spots), PB1 (green spots), PA (orange spots), and NP (yellow spots). The nucleus is labeled in blue based on DAPI staining. Lakdawala et al.

Image Credit: Seema S. Lakdawala and Juraj Kabat, NIAID, NIH.