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Research Article

Temperature Shift and Host Cell Contact Up-Regulate Sporozoite Expression of Plasmodium falciparum Genes Involved in Hepatocyte Infection

  • Anthony Siau,

    Affiliations: INSERM, U511, Paris, France, Université Pierre et Marie Curie-Paris 6, UMR S511 Paris, France

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  • Olivier Silvie equal contributor,

    equal contributor Contributed equally to this work with: Olivier Silvie, Jean-François Franetich

    Affiliations: INSERM, U511, Paris, France, Université Pierre et Marie Curie-Paris 6, UMR S511 Paris, France

    These authors contributed equally to directing this work.

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  • Jean-François Franetich equal contributor,

    equal contributor Contributed equally to this work with: Olivier Silvie, Jean-François Franetich

    Affiliations: INSERM, U511, Paris, France, Université Pierre et Marie Curie-Paris 6, UMR S511 Paris, France

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  • Samir Yalaoui,

    Affiliations: INSERM, U511, Paris, France, Université Pierre et Marie Curie-Paris 6, UMR S511 Paris, France

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  • Carine Marinach,

    Affiliations: INSERM, U511, Paris, France, Université Pierre et Marie Curie-Paris 6, UMR S511 Paris, France

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  • Laurent Hannoun,

    Affiliation: Service de Chirurgie Digestive, Hépato-Bilio-Pancréatique et Transplantation Hépatique, Hôpital Pitié-Salpêtrière, Paris, France

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  • Geert-Jaan van Gemert,

    Affiliation: Department of Medical Microbiology, University Medical Centre, Nijmegen, The Netherlands

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  • Adrian J. F. Luty,

    Affiliation: Department of Medical Microbiology, University Medical Centre, Nijmegen, The Netherlands

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  • Emmanuel Bischoff,

    Affiliation: PF2-Genopole, Institut Pasteur, Paris France

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  • Peter H. David,

    Affiliation: Unité d'Immunologie Moléculaire des Parasites, CNRS URA 2581, Département de Parasitologie, Institut Pasteur, Paris, France

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  • Georges Snounou,

    Affiliation: Laboratoire de Parasitologie Comparée et Modèles Expérimentaux, Muséum National d'Histoire Naturelle, Paris, France

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  • Catherine Vaquero,

    Affiliations: INSERM, U511, Paris, France, Université Pierre et Marie Curie-Paris 6, UMR S511 Paris, France

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  • Patrick Froissard,

    Affiliations: INSERM, U511, Paris, France, Université Pierre et Marie Curie-Paris 6, UMR S511 Paris, France

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  • Dominique Mazier mail

    mazier@chups.jussieu.fr

    Affiliations: INSERM, U511, Paris, France, Université Pierre et Marie Curie-Paris 6, UMR S511 Paris, France, AP-HP, Groupe hospitalier Pitié-Salpêtrière, Service Parasitologie-Mycologie, Paris, France

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  • Published: August 08, 2008
  • DOI: 10.1371/journal.ppat.1000121

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