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Research Article

An Amphipathic α-Helix Controls Multiple Roles of Brome Mosaic Virus Protein 1a in RNA Replication Complex Assembly and Function

  • Ling Liu,

    Affiliation: Institute for Molecular Virology, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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  • William M. Westler,

    Affiliations: National Magnetic Resonance Facility, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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  • Johan A. den Boon,

    Affiliation: Institute for Molecular Virology, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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  • Xiaofeng Wang,

    Affiliation: Institute for Molecular Virology, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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  • Arturo Diaz,

    Affiliation: Institute for Molecular Virology, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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  • H. Adam Steinberg,

    Affiliation: Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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  • Paul Ahlquist mail

    ahlquist@wisc.edu

    Affiliations: Institute for Molecular Virology, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Howard Hughes Medical Institute, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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  • Published: March 27, 2009
  • DOI: 10.1371/journal.ppat.1000351

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