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Research Article

The Nicotinic Acetylcholine Receptors of the Parasitic Nematode Ascaris suum: Formation of Two Distinct Drug Targets by Varying the Relative Expression Levels of Two Subunits

  • Sally M. Williamson,

    Affiliation: Department of Biology & Biochemistry, University of Bath, Bath, United Kingdom

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  • Alan P. Robertson,

    Affiliation: Department of Biomedical Sciences, Iowa State University, Ames, Iowa, United States of America

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  • Laurence Brown,

    Affiliation: MRC Functional Genomics Unit, Oxford, United Kingdom

    Current address: Department of Ophthalmology, University of Oxford, Oxford, United Kingdom

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  • Tracey Williams,

    Affiliation: Veterinary Medicine Research & Development, Pfizer Animal Health, Kalamazoo, Michigan, United States of America

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  • Debra J. Woods,

    Affiliation: Veterinary Medicine Research & Development, Pfizer Animal Health, Kalamazoo, Michigan, United States of America

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  • Richard J. Martin,

    Affiliation: Department of Biomedical Sciences, Iowa State University, Ames, Iowa, United States of America

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  • David B. Sattelle,

    Affiliation: MRC Functional Genomics Unit, Oxford, United Kingdom

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  • Adrian J. Wolstenholme mail

    adrianw@uga.edu

    Affiliation: Department of Biology & Biochemistry, University of Bath, Bath, United Kingdom

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  • Published: July 17, 2009
  • DOI: 10.1371/journal.ppat.1000517

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