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Research Article

Mycobacterium tuberculosis WhiB3 Maintains Redox Homeostasis by Regulating Virulence Lipid Anabolism to Modulate Macrophage Response

  • Amit Singh,

    Affiliation: Department of Microbiology, Centers for Free Radical Biology, AIDS Research, and Emerging Infections and Emergency Preparedness, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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  • David K. Crossman,

    Affiliation: Department of Microbiology, Centers for Free Radical Biology, AIDS Research, and Emerging Infections and Emergency Preparedness, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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  • Deborah Mai,

    Affiliation: Department of Microbiology, Centers for Free Radical Biology, AIDS Research, and Emerging Infections and Emergency Preparedness, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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  • Loni Guidry,

    Affiliation: Department of Microbiology, Centers for Free Radical Biology, AIDS Research, and Emerging Infections and Emergency Preparedness, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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  • Martin I. Voskuil,

    Affiliation: Department of Microbiology, University of Colorado Denver, School of Medicine, Aurora, Colorado, United States of America

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  • Matthew B. Renfrow,

    Affiliation: Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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  • Adrie J. C. Steyn mail

    asteyn@uab.edu

    Affiliation: Department of Microbiology, Centers for Free Radical Biology, AIDS Research, and Emerging Infections and Emergency Preparedness, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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  • Published: August 14, 2009
  • DOI: 10.1371/journal.ppat.1000545

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    23 Aug 2009
    19:12 GMT
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    Posted by viks on 23 Aug 2009 at 19:12 GMT