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Research Article

Proteolysis of Human Thrombin Generates Novel Host Defense Peptides

  • Praveen Papareddy,

    Affiliation: Division of Dermatology and Venereology, Department of Clinical Sciences, Lund University, Biomedical Center, Lund, Sweden

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  • Victoria Rydengård,

    Affiliation: Division of Dermatology and Venereology, Department of Clinical Sciences, Lund University, Biomedical Center, Lund, Sweden

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  • Mukesh Pasupuleti,

    Affiliation: Division of Dermatology and Venereology, Department of Clinical Sciences, Lund University, Biomedical Center, Lund, Sweden

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  • Björn Walse,

    Affiliation: SARomics AB, Lund, Sweden

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  • Matthias Mörgelin,

    Affiliation: Division of Infection Medicine, Department of Clinical Sciences, Lund University, Biomedical Center, Lund, Sweden

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  • Anna Chalupka,

    Affiliations: Division of Dermatology and Venereology, Department of Clinical Sciences, Lund University, Biomedical Center, Lund, Sweden, Department of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland

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  • Martin Malmsten,

    Affiliation: Department of Pharmacy, Uppsala University, Biomedical Center, Uppsala, Sweden

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  • Artur Schmidtchen mail

    artur.schmidtchen@med.lu.se

    Affiliation: Division of Dermatology and Venereology, Department of Clinical Sciences, Lund University, Biomedical Center, Lund, Sweden

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  • Published: April 22, 2010
  • DOI: 10.1371/journal.ppat.1000857

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