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Research Article

EspA Acts as a Critical Mediator of ESX1-Dependent Virulence in Mycobacterium tuberculosis by Affecting Bacterial Cell Wall Integrity

  • Alejandra Garces equal contributor,

    equal contributor Contributed equally to this work with: Alejandra Garces, Krishnamohan Atmakuri

    Affiliation: Harvard School of Public Health, Department of Immunology and Infectious Diseases, Boston, Massachusetts, United States of America

    X
  • Krishnamohan Atmakuri equal contributor,

    equal contributor Contributed equally to this work with: Alejandra Garces, Krishnamohan Atmakuri

    Affiliation: Harvard School of Public Health, Department of Immunology and Infectious Diseases, Boston, Massachusetts, United States of America

    X
  • Michael R. Chase,

    Affiliation: Harvard School of Public Health, Department of Immunology and Infectious Diseases, Boston, Massachusetts, United States of America

    X
  • Joshua S. Woodworth,

    Affiliation: Brigham and Women's Hospital, Division of Rheumatology, Boston, Massachusetts, United States of America

    X
  • Bryan Krastins,

    Affiliation: Thermo Fisher Scientific, BRIMS Unit, Cambridge, Massachusetts, United States of America

    X
  • Alissa C. Rothchild,

    Affiliation: Brigham and Women's Hospital, Division of Rheumatology, Boston, Massachusetts, United States of America

    X
  • Talia L. Ramsdell,

    Affiliation: Harvard School of Public Health, Department of Immunology and Infectious Diseases, Boston, Massachusetts, United States of America

    X
  • Mary F. Lopez,

    Affiliation: Thermo Fisher Scientific, BRIMS Unit, Cambridge, Massachusetts, United States of America

    X
  • Samuel M. Behar,

    Affiliation: Brigham and Women's Hospital, Division of Rheumatology, Boston, Massachusetts, United States of America

    X
  • David A. Sarracino,

    Affiliation: Thermo Fisher Scientific, BRIMS Unit, Cambridge, Massachusetts, United States of America

    X
  • Sarah M. Fortune mail

    sfortune@hsph.harvard.edu

    Affiliation: Harvard School of Public Health, Department of Immunology and Infectious Diseases, Boston, Massachusetts, United States of America

    X
  • Published: June 24, 2010
  • DOI: 10.1371/journal.ppat.1000957

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