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Research Article

A Novel CCR5 Mutation Common in Sooty Mangabeys Reveals SIVsmm Infection of CCR5-Null Natural Hosts and Efficient Alternative Coreceptor Use In Vivo

  • Nadeene E. Riddick,

    Affiliations: Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America, Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Emilia A. Hermann,

    Affiliation: Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Lamorris M. Loftin,

    Affiliations: Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America, Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Sarah T. Elliott,

    Affiliations: Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America, Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Winston C. Wey,

    Affiliation: Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Barbara Cervasi,

    Affiliation: Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Jessica Taaffe,

    Affiliations: Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Jessica C. Engram,

    Affiliation: Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Bing Li,

    Affiliation: Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America

    X
  • James G. Else,

    Affiliation: Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America

    X
  • Yingying Li,

    Affiliation: Departments of Medicine and Microbiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

    X
  • Beatrice H. Hahn,

    Affiliation: Departments of Medicine and Microbiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

    X
  • Cynthia A. Derdeyn,

    Affiliations: Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America, Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia, United States of America

    X
  • Donald L. Sodora,

    Affiliation: Seattle Biomedical Research Institute, Seattle, Washington, United States of America

    X
  • Cristian Apetrei,

    Affiliation: Department of Microbiology and Molecular Genetics, University of Pittsburgh Center for Vaccine Research, Pittsburgh, Pennsylvania, United States of America

    X
  • Mirko Paiardini,

    Affiliation: Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

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  • Guido Silvestri,

    Affiliation: Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Ronald G. Collman mail

    collmanr@mail.med.upenn.edu

    Affiliations: Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America, Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Published: August 26, 2010
  • DOI: 10.1371/journal.ppat.1001064

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