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Research Article

Pathogenic Bacteria Target NEDD8-Conjugated Cullins to Hijack Host-Cell Signaling Pathways

  • Grégory Jubelin equal contributor,

    equal contributor Contributed equally to this work with: Grégory Jubelin, Frédéric Taieb

    Affiliations: INRA, UMR 1225, Toulouse, France, Université de Toulouse; ENVT; UMR 1225; Toulouse, France

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  • Frédéric Taieb equal contributor,

    equal contributor Contributed equally to this work with: Grégory Jubelin, Frédéric Taieb

    Affiliations: INRA, UMR 1225, Toulouse, France, Université de Toulouse; ENVT; UMR 1225; Toulouse, France

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  • David M. Duda,

    Affiliation: Howard Hughes Medical Institute, St. Jude Children's Research Hospital, Department of Structural Biology, Memphis, Tennessee, United States of America

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  • Yun Hsu,

    Affiliation: Laboratory of Structural Microbiology, Rockefeller University, New York, New York, United States of America

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  • Ascel Samba-Louaka,

    Affiliations: INRA, UMR 1225, Toulouse, France, Université de Toulouse; ENVT; UMR 1225; Toulouse, France

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  • Rika Nobe,

    Affiliations: INRA, UMR 1225, Toulouse, France, Université de Toulouse; ENVT; UMR 1225; Toulouse, France

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  • Marie Penary,

    Affiliations: INRA, UMR 1225, Toulouse, France, Université de Toulouse; ENVT; UMR 1225; Toulouse, France

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  • Claude Watrin,

    Affiliations: INRA, UMR 1225, Toulouse, France, Université de Toulouse; ENVT; UMR 1225; Toulouse, France

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  • Jean-Philippe Nougayrède,

    Affiliations: INRA, UMR 1225, Toulouse, France, Université de Toulouse; ENVT; UMR 1225; Toulouse, France

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  • Brenda A. Schulman,

    Affiliation: Howard Hughes Medical Institute, St. Jude Children's Research Hospital, Department of Structural Biology, Memphis, Tennessee, United States of America

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  • C. Erec Stebbins mail,

    stebbins@rockefeller.edu (CES); e.oswald@envt.fr (EO)

    Affiliation: Laboratory of Structural Microbiology, Rockefeller University, New York, New York, United States of America

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  • Eric Oswald mail

    stebbins@rockefeller.edu (CES); e.oswald@envt.fr (EO)

    Affiliations: INRA, UMR 1225, Toulouse, France, Université de Toulouse; ENVT; UMR 1225; Toulouse, France, Université de Toulouse; UPS; Faculté de Médecine; Toulouse, France, CHU de Toulouse; Institut Fédératif de Biologie; Laboratoire de Bactériologie-Hygiène; Toulouse, France

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  • Published: September 30, 2010
  • DOI: 10.1371/journal.ppat.1001128

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