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Research Article

The Coxsackievirus B 3Cpro Protease Cleaves MAVS and TRIF to Attenuate Host Type I Interferon and Apoptotic Signaling

  • Amitava Mukherjee,

    Affiliation: Department of Cell Biology and Physiology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    X
  • Stefanie A. Morosky,

    Affiliation: Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    X
  • Elizabeth Delorme-Axford,

    Affiliation: Department of Cell Biology and Physiology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    X
  • Naomi Dybdahl-Sissoko,

    Affiliation: Picornavirus Laboratory, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

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  • M. Steven Oberste,

    Affiliation: Picornavirus Laboratory, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

    X
  • Tianyi Wang,

    Affiliation: Department of Infectious Diseases and Microbiology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    X
  • Carolyn B. Coyne mail

    coynec2@pitt.edu

    Affiliation: Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    X
  • Published: March 10, 2011
  • DOI: 10.1371/journal.ppat.1001311

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