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Research Article

On Being the Right Size: The Impact of Population Size and Stochastic Effects on the Evolution of Drug Resistance in Hospitals and the Community

  • Roger D. Kouyos equal contributor mail,

    equal contributor Contributed equally to this work with: Roger D. Kouyos, Pia Abel zur Wiesch

    rkouyos@princeton.edu

    Affiliations: Institute of Integrative Biology, ETH Zurich, Zurich, Switzerland, Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America

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  • Pia Abel zur Wiesch equal contributor,

    equal contributor Contributed equally to this work with: Roger D. Kouyos, Pia Abel zur Wiesch

    Affiliation: Institute of Integrative Biology, ETH Zurich, Zurich, Switzerland

    X
  • Sebastian Bonhoeffer

    Affiliation: Institute of Integrative Biology, ETH Zurich, Zurich, Switzerland

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  • Published: April 14, 2011
  • DOI: 10.1371/journal.ppat.1001334

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