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Research Article

Plasmacytoid Dendritic Cells Sequester High Prion Titres at Early Stages of Prion Infection

  • Rocio Castro-Seoane,

    Affiliation: MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom

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  • Holger Hummerich,

    Affiliation: MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom

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  • Trevor Sweeting,

    Affiliation: Department of Statistical Science, University College London, London, United Kingdom

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  • M. Howard Tattum,

    Affiliation: MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom

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  • Jacqueline M. Linehan,

    Affiliation: MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom

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  • Mar Fernandez de Marco,

    Affiliation: MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom

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  • Sebastian Brandner,

    Affiliation: MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom

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  • John Collinge,

    Affiliation: MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom

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  • Peter-Christian Klöhn mail

    p.kloehn@prion.ucl.ac.uk

    Affiliation: MRC Prion Unit and Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom

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  • Published: February 16, 2012
  • DOI: 10.1371/journal.ppat.1002538

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